Chen John J, Bhatti M Tariq, Bradley Elizabeth, Garrity James, Thurtell Matthew J
Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA.
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
Neuroophthalmology. 2019 May 28;44(1):11-15. doi: 10.1080/01658107.2019.1615959. eCollection 2020 Feb.
Patients with syphilis can present with optic disc oedema (ODE) without visual compromise, which has been primarily attributed to papilloedema from raised intracranial pressure or optic perineuritis from optic nerve sheath inflammation. We report four cases of ODE in the setting of syphilis with preserved visual function, normal intracranial pressure, and no enhancement of the optic nerve or sheath on magnetic resonance imaging. We propose the term "incipient syphilitic papillitis" for cases presenting with ODE, preserved vision and absence of optic nerve sheath enhancement, which is likely a more common presentation than syphilitic optic perineuritis.
梅毒患者可出现视盘水肿（ODE）但无视力损害，这主要归因于颅内压升高引起的视乳头水肿或视神经鞘炎症引起的视神经周围炎。我们报告了4例梅毒患者出现ODE，视力功能保留，颅内压正常，磁共振成像显示视神经或视神经鞘无强化。对于出现ODE、视力保留且视神经鞘无强化的病例，我们提出“早期梅毒性视乳头炎”这一术语，它可能比梅毒性视神经周围炎更常见。
