Rosado Steeve Neves, Silveira Vera, Reis Ana Isabel, Gordinho André, Noronha Carla
Internal Medicine Residents, on Final Year - Beatriz Ângelo Hospital, Loures, Portugal.
Consultant in Internal Medicine - Beatriz Ângelo Hospital, Loures, Portugal.
Eur J Case Rep Intern Med. 2018 Jun 26;5(6):000855. doi: 10.12890/2018_000855. eCollection 2018.
Primary Sjögren's syndrome (SS) is a chronic, systemic autoimmune disease, most commonly presenting with sicca symptoms-xerostomia and xerophthalmia. Up to one-half of affected individuals also develop extra-glandular involvement. Early diagnosis is important to prevent further complications. This paper describes an atypical case of SS in a 21-year-old woman who presented first with neuropsychiatric symptoms and fever. She was diagnosed and treated for a presumed psychotic episode. However, because she remained febrile, a thorough investigation resulted in the challenging diagnosis of SS.
Primary Sjögren's syndrome (SS) may be an under-recognized cause of central nervous system and neuropsychiatric involvement.Neuropsychiatric manifestations of primary SS can be variable.Patients may be treated incorrectly if the diagnosis is not rapidly established, so a clinical history and thorough examination are very important.
原发性干燥综合征（SS）是一种慢性全身性自身免疫性疾病，最常见的表现为口干、眼干等干燥症状。多达一半的患者还会出现腺外受累。早期诊断对于预防进一步并发症很重要。本文描述了一名21岁女性的非典型干燥综合征病例，该患者最初表现为神经精神症状和发热。她被诊断为疑似精神病发作并接受治疗。然而，由于她持续发热，经过全面检查后确诊为具有挑战性的干燥综合征。
原发性干燥综合征（SS）可能是中枢神经系统和神经精神受累的一个未被充分认识的原因。原发性干燥综合征的神经精神表现可能多种多样。如果不能迅速确诊，患者可能会接受错误的治疗，因此临床病史和全面检查非常重要。
