Farrukh Larabe, Mumtaz Aqsa, Wajid Sumbal, Waqar Hafiza Hareem, Peredo-Wende Ruben
Internal Medicine, Albany Medical Center, Albany, USA.
Internal Medicine, Montefiore St. Luke's Cornwall Hospital, Newburgh, USA.
Cureus. 2023 Jun 26;15(6):e41002. doi: 10.7759/cureus.41002. eCollection 2023 Jun.
Sjogren's syndrome (SS) is a chronic inflammatory disorder of the exocrine glands. It is characterized by a lymphocytic infiltrate in the lacrimal and salivary glands causing keratoconjunctivitis sicca and xerostomia. Extra-glandular involvement may be present in about one-third of patients with primary Sjogren's syndrome (pSS). The most commonly affected organs are the thyroid, lungs, gastrointestinal tract, kidneys, skin, and nervous system. Cardiac manifestations of Sjogren's syndrome are rare and not well-described in the current literature. Most of the evidence is present in the form of case reports and small case series. However, recent studies have shown that patients with Sjogren's syndrome (SS) seem to have a greater overall risk of cardiovascular (CV) events. Although not conventionally considered a feature of the disease, cardiac manifestations can lead to increased morbidity and mortality in this patient population. In this review article, we study the association between cardiac diseases and primary Sjogren's syndrome.
干燥综合征（SS）是一种外分泌腺的慢性炎症性疾病。其特征是泪腺和唾液腺出现淋巴细胞浸润，导致干眼症和口干症。约三分之一的原发性干燥综合征（pSS）患者可能存在腺外受累。最常受累的器官是甲状腺、肺、胃肠道、肾脏、皮肤和神经系统。干燥综合征的心脏表现较为罕见，目前文献中对此描述不多。大多数证据以病例报告和小病例系列的形式呈现。然而，最近的研究表明，干燥综合征（SS）患者似乎总体上发生心血管（CV）事件的风险更高。尽管心脏表现通常不被视为该疾病的特征，但在这一患者群体中，心脏表现可导致发病率和死亡率增加。在这篇综述文章中，我们研究了心脏病与原发性干燥综合征之间的关联。
