Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.
Laryngoscope. 2019 Oct;129(10):2361-2365. doi: 10.1002/lary.27861. Epub 2019 Feb 12.
To evaluate the safety of office-based calcium hydroxylapatite (CaHA) injection laryngoplasty via the cricothyroid approach through an analysis of all procedures performed over a period of 10 years at a single institution.
In total, 962 office-based CaHA injection laryngoplasty via the cricothyroid approach procedures were performed by a single physician at our institution between 2007 and 2016. From these, 955 procedures performed in 617 patients were included in our analysis. The medical records of all 617 patients were retrospectively reviewed. We classified all procedure-related complications according to the time of onset. Complications that occurred during the procedure were considered intraprocedural complications, whereas complications that developed within 1 week after injection and those that developed after 1 week and were recorded more than twice in the medical records were considered acute and delayed complications, respectively. Failed cases were categorized separately as failure.
Five cases were failed (0.5%). Intraprocedural complications included superficial injection in eight cases (0.8%). Acute and delayed onset of dyspnea was observed in three (0.3%) and two (0.2%) cases, respectively. The incidence of failures and major complications requiring active intervention was 1.6%.
Our findings suggest that office-based CaHA injection laryngoplasty via the cricothyroid approach is as safe as conventional transoral injection laryngoplasty.
4 Laryngoscope, 129:2361-2365, 2019.
通过对一家机构 10 年来所有手术的分析，评估经环甲膜入路行局麻下羟基磷灰石（CaHA）注射式喉成形术的安全性。
在 2007 年至 2016 年间，一位医生在我院共进行了 962 例经环甲膜入路行局麻下 CaHA 注射式喉成形术，其中 955 例在 617 例患者中进行了分析。回顾性分析了这 617 例患者的所有病历。我们根据发病时间对所有与手术相关的并发症进行了分类。术中发生的并发症被认为是术中并发症，而注射后 1 周内发生和记录在病历中超过两次的急性和延迟并发症则分别被认为是急性和延迟并发症。失败病例单独归类为失败。
5 例失败（0.5%）。8 例（0.8%）出现浅层注射，3 例（0.3%）出现急性呼吸困难，2 例（0.2%）出现延迟呼吸困难。失败和需要积极干预的主要并发症的发生率为 1.6%。
我们的研究结果表明，经环甲膜入路行局麻下 CaHA 注射式喉成形术与传统经口注射式喉成形术一样安全。
4 Laryngoscope, 129:2361-2365, 2019.
