Koçdor Pelin, Tulunay-Uğur Özlem E
Department of Otolaryngology, University of Arkansas For Medical Sciences, Little Rock, AR, USA.
Kulak Burun Bogaz Ihtis Derg. 2014 Sep-Oct;24(5):271-5. doi: 10.5606/kbbihtisas.2014.65807.
This study aims to evaluate our injection laryngoplasty experience in patients with unilateral vocal fold paralysis.
Sixty-eight patients (32 males, 36 females; mean age 59.5 years; range 27 to 86 years) who were diagnosed with unilateral vocal fold paralysis at our clinic and who underwent injection laryngoplasty using calcium hydroxylapatite between January 2005 and June 2012 were included in this study.
Mean follow-up period was 36 weeks (range 0-340.4 weeks). Data of 29 patients with post-injection Voice Handicap Index (VHI) scores were retrospectively analyzed. Of these patients, 16 (55%) were female, and the mean patient age was 60 (range 27 to 86 years). Seventeen patients underwent suspension laryngoscopy in the operating room, 12 patients underwent in-office percutaneous injection. Post-injection mean VHI score was 36.7 (range 4 to 87). Percutaneous injection laryngoplasty was performed to half of the 20 patients with pre- and post-injection VHI data. Mean VHI scores of these 20 patients improved by 27.9 points. Mean VHI score improved by 35.1 points in the percutaneous group, and by 20.7 points in the suspension group (p=0.29). Post-injection VHI score of one patient with lung cancer decreased, as his general health deteriorated.
This study supports injection laryngoplasty in vocal fold paralysis. Calcium hydroxylapatite is a safe and effective treatment method in both percutaneous and operating room procedures.
本研究旨在评估我们在单侧声带麻痹患者中进行注射喉成形术的经验。
纳入2005年1月至2012年6月期间在我院被诊断为单侧声带麻痹且接受羟基磷灰石注射喉成形术的68例患者（男性32例，女性36例；平均年龄59.5岁；年龄范围27至86岁）。
平均随访期为36周（范围0 - 340.4周）。对29例注射后嗓音障碍指数（VHI）评分患者的数据进行回顾性分析。这些患者中，16例（55%）为女性，平均年龄60岁（范围27至86岁）。17例患者在手术室接受了支撑喉镜检查，12例患者接受了门诊经皮注射。注射后平均VHI评分为36.7（范围4至87）。20例有注射前后VHI数据的患者中有一半接受了经皮注射喉成形术。这20例患者的平均VHI评分提高了27.9分。经皮组平均VHI评分提高35.1分，支撑喉镜检查组提高20.7分（p = 0.29）。1例肺癌患者注射后VHI评分下降，因其总体健康状况恶化。
本研究支持在声带麻痹中进行注射喉成形术。羟基磷灰石在经皮和手术室操作中都是一种安全有效的治疗方法。
