1 University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
2 Alexor Inc, Morrisville, NC, USA.
Ann Pharmacother. 2019 Jul;53(7):683-689. doi: 10.1177/1060028019831259. Epub 2019 Feb 13.
Many adolescents do not obtain the maximum benefit from their asthma medications. Improving patient-provider communication may improve adolescents' asthma knowledge, adherence, and clinical outcomes.
To determine how a question prompt list and educational video intervention affect youth- and caregiver-reported medication adherence and self-reported medication problems.
Adolescents with persistent asthma (n = 359; 56.4% with moderate to severe asthma) and their caregivers were enrolled in a randomized controlled trial at 4 pediatric clinics. Intervention group families received a question prompt list and watched a short video before seeing the provider; control families received usual care. Youth- and caregiver-reported medication adherence was measured with a Visual Analog Scale, ranging from 0 to 100. Generalized estimating equations were used to determine how the intervention and covariates were associated with medication adherence and reported problems at 12 months.
The intervention was not a significant predictor of medication adherence at 12 months. Higher caregiver education was associated with higher youth-reported adherence (β = 1.1; 95% CI = 0.1, 2.1; P = 0.036) and caregiver-reported adherence (β = 1.2; 95% CI = 0.3, 2.0; P = 0.006). The intervention was associated with fewer caregiver-reported problems at 12 months (β = -0.32; 95% CI = -0.48, -0.16; P < 0.001).
A question prompt list and educational video decreased the number of caregiver-reported medication problems, but did not significantly affect medication adherence. Further research is needed to develop more effective interventions to improve medication adherence and outcomes.
许多青少年无法从哮喘药物治疗中获得最大益处。改善医患沟通可能会提高青少年的哮喘知识、治疗依从性和临床结局。
确定问题提示清单和教育视频干预如何影响青少年和照顾者报告的药物依从性以及自我报告的药物问题。
在 4 家儿科诊所,招募了患有持续性哮喘的青少年(n=359;56.4%患有中重度哮喘)及其照顾者,将其纳入一项随机对照试验。干预组家庭在与提供者见面之前收到问题提示清单并观看了一个短视频;对照组家庭接受常规护理。青少年和照顾者报告的药物依从性通过视觉模拟量表进行测量,范围为 0 到 100。使用广义估计方程确定干预和协变量如何与 12 个月时的药物依从性和报告的问题相关。
干预措施在 12 个月时并不是药物依从性的显著预测因素。照顾者的受教育程度较高与青少年报告的更高的依从性(β=1.1;95%置信区间为 0.1,2.1;P=0.036)和照顾者报告的依从性(β=1.2;95%置信区间为 0.3,2.0;P=0.006)相关。干预组在 12 个月时报告的问题更少(β=-0.32;95%置信区间为-0.48,-0.16;P<0.001)。
问题提示清单和教育视频减少了照顾者报告的药物问题数量,但并未显著影响药物依从性。需要进一步研究以开发更有效的干预措施,以提高药物依从性和改善结局。