Faculty of Medicine, Rzeszow University, Rzeszow, Poland.
St. Louis Regional Specialized Children's Hospital, Cracow, Poland.
Adv Exp Med Biol. 2019;1153:101-107. doi: 10.1007/5584_2019_344.
A worrying increase in the number of measles cases has been noted recently in Poland, which may have to do with a decreasing proportion of children vaccinated against measles, mumps, and rubella (MMR) in the second year of life (<95%). For many years, MMR vaccination in children has been associated with a fear of allergy to eggs. This study seeks to define the reason and justification for postponing MMR vaccination in a population of children referred to the outpatient specialist immunization clinic. One hundred and thirty eight (138) children, mean 24.5 ± 26.6 months, with a history of past allergies, in whom the first-time MMR vaccination was delayed by family doctors for fear of allergic reactions, were enrolled into the study. The mean delay in a vaccine shot was 12.3 ± 26.9 months. There were 101 children who displayed a distinct allergy to the egg proteins, among other accompanying types of allergy. All of the 138 children were found eligible to receive MMR vaccine at the visit to the clinic. No early allergic responses were noticed in any of the children. There were negligible delayed allergic responses in six children, all from the egg allergy group. We conclude that MMR vaccination in children with egg allergy is safe and can be conducted on the outpatient basis without any specific precautions or safety measures. Delays in vaccination were unjustified and may jeopardize children's health. There is a need for insightful education of primary care doctors concerning of MMR vaccination safety, particularly when allergy is suspected, to avoid unduly and potentially harmful delays.
最近在波兰注意到麻疹病例数量令人担忧地增加，这可能与第二年生命中接种麻疹、腮腺炎和风疹（MMR）疫苗的儿童比例下降（<95%）有关。多年来，儿童接种 MMR 疫苗一直与对鸡蛋过敏的恐惧有关。本研究旨在确定将 MMR 疫苗接种推迟到门诊专科免疫接种诊所就诊的儿童人群中的原因和理由。招募了 138 名（138 名）有过敏史的儿童，平均年龄为 24.5±26.6 个月，由于家庭医生担心过敏反应，首次 MMR 疫苗接种被推迟。疫苗接种的平均延迟时间为 12.3±26.9 个月。有 101 名儿童对鸡蛋蛋白显示出明显的过敏反应，还有其他伴随类型的过敏反应。所有 138 名儿童在就诊时均被发现符合接受 MMR 疫苗的条件。在任何儿童中均未发现早期过敏反应。在 6 名儿童中，只有 6 名来自鸡蛋过敏组，出现了轻微的延迟过敏反应。我们的结论是，对鸡蛋过敏的儿童进行 MMR 疫苗接种是安全的，可以在门诊基础上进行，无需采取任何特殊预防措施或安全措施。疫苗接种的延迟是不合理的，可能会危及儿童的健康。有必要对初级保健医生进行有关 MMR 疫苗接种安全性的深入教育，特别是在怀疑过敏的情况下，以避免不必要和潜在有害的延迟。
