Department of Systems Biology, Yonsei University, Seoul 03722, Korea.
BMB Rep. 2019 Mar;52(3):175-180. doi: 10.5483/BMBRep.2019.52.3.047.
Telomeres are nucleoprotein complexes at the physical ends of linear eukaryotic chromosomes. They protect the chromosome ends from various external attacks to avoid the loss of genetic information. Telomeres are maintained by cellular activities associated with telomerase and telomerebinding proteins. In addition, epigenetic regulators have pivotal roles in controlling the chromatin state at the telomeres and the subtelomeric regions, contributing to the maintenance of chromosomal homeostasis in yeast, animals, and plants. Here, we review the recent findings on chromatin modifications possibly associated with the dynamic states of telomeres in Arabidopsis thaliana. [BMB Reports 2019; 52(3): 175-180].
端粒是线性真核染色体物理末端的核蛋白复合物。它们保护染色体末端免受各种外部攻击，以避免遗传信息的丢失。端粒由与端粒酶和端粒结合蛋白相关的细胞活动维持。此外，表观遗传调节剂在控制端粒和亚端粒区域的染色质状态方面发挥着关键作用，有助于维持酵母、动物和植物中的染色体动态平衡。在这里，我们综述了最近关于拟南芥中端粒动态状态相关的染色质修饰的发现。[BMB 报告 2019;52(3):175-180]。
