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Sirtuins in epigenetic regulation.

作者信息

Jing Hui, Lin Hening

机构信息

Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14850, United States.

出版信息

Chem Rev. 2015 Mar 25;115(6):2350-75. doi: 10.1021/cr500457h. Epub 2015 Jan 28.

DOI:10.1021/cr500457h
PMID:25804908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4610301/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d6a/4610301/86895f8b55bd/cr-2014-00457h_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d6a/4610301/e52d5cd3ee96/cr-2014-00457h_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d6a/4610301/084186ea9a74/cr-2014-00457h_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d6a/4610301/86895f8b55bd/cr-2014-00457h_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d6a/4610301/e52d5cd3ee96/cr-2014-00457h_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d6a/4610301/084186ea9a74/cr-2014-00457h_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d6a/4610301/86895f8b55bd/cr-2014-00457h_0003.jpg

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Sirtuins in epigenetic regulation.

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[3]
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[6]
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[7]
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本文引用的文献

[1]
Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism.

Cell. 2014-7-31

[2]
MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer.

Sci Signal. 2014-7-29

[3]
Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion.

Proc Natl Acad Sci U S A. 2014-7-9

[4]
Sirtuin inhibitors as anticancer agents.

Future Med Chem. 2014-5

[5]
SIRT1 mediates FOXA2 breakdown by deacetylation in a nutrient-dependent manner.

PLoS One. 2014-5-29

[6]
The involvement of NFAT transcriptional activity suppression in SIRT1-mediated inhibition of COX-2 expression induced by PMA/Ionomycin.

PLoS One. 2014-5-23

[7]
SIRT2 induces the checkpoint kinase BubR1 to increase lifespan.

EMBO J. 2014-7-1

[8]
SIRT2 as a new player in epigenetic programming of keratinocyte differentiation and a candidate tumor suppressor.

Exp Dermatol. 2014-9

[9]
ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation.

Cell Death Differ. 2014-8

[10]
Oxidative stress activates SIRT2 to deacetylate and stimulate phosphoglycerate mutase.

Cancer Res. 2014-5-1

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