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酷似乳腺癌锁骨上淋巴结转移的梭形细胞肉瘤

Spindle Cell Sarcoma Mimicking Supraclavicular Lymph Node Metastasis of Breast Cancer.

作者信息

Paek Se Hyun, Lee Kyoung Eun, Kim Han Su, Woo Joohyun, Lim Woosung

机构信息

Department of Surgery, College of Medicine, Ewha Womans University, Seoul, South Korea.

Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, South Korea.

出版信息

Am J Case Rep. 2019 Feb 14;20:194-197. doi: 10.12659/AJCR.913581.

DOI:10.12659/AJCR.913581
PMID:30760697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6388761/
Abstract

BACKGROUND Sarcomas can develop de novo or secondary to radiotherapy after or during breast cancer treatment. Diagnosis can be challenging, as such, a sarcoma is often missed on routine follow-up imaging and often presents with dermatologic findings. CASE REPORT Here, we present a case of a 45-year-old female who developed spindle cell sarcoma on her neck, which was mimicking supraclavicular lymph node metastasis of breast cancer. CONCLUSIONS Based on our report, we recommend a tissue biopsy with an immunohistochemistry profile when a mass suspicious for metastasis is found in patients with breast cancer.

摘要

背景

肉瘤可原发发生,或继发于乳腺癌治疗期间或之后的放疗。诊断可能具有挑战性,因此,肉瘤在常规随访影像学检查中常被漏诊,且常伴有皮肤表现。病例报告:在此,我们报告一例45岁女性,其颈部发生梭形细胞肉瘤,酷似乳腺癌锁骨上淋巴结转移。结论:基于我们的报告,我们建议在乳腺癌患者中发现可疑转移肿块时进行组织活检并进行免疫组化分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a6/6388761/c529b543157e/amjcaserep-20-194-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a6/6388761/488e94ba2b06/amjcaserep-20-194-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a6/6388761/c529b543157e/amjcaserep-20-194-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a6/6388761/488e94ba2b06/amjcaserep-20-194-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1a6/6388761/c529b543157e/amjcaserep-20-194-g002.jpg

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本文引用的文献

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Spindle cell sarcoma: a SEER population-based analysis.梭形细胞肉瘤:一项 SEER 基于人群的分析。
Sci Rep. 2018 Mar 22;8(1):5024. doi: 10.1038/s41598-018-23145-4.
2
New insights into the metastatic behavior after breast cancer surgery, according to well-established clinicopathological variables and molecular subtypes.根据成熟的临床病理变量和分子亚型,对乳腺癌手术后转移行为的新见解。
PLoS One. 2017 Sep 18;12(9):e0184680. doi: 10.1371/journal.pone.0184680. eCollection 2017.
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Spindle cell carcinoma: the general demographics, basic clinico-pathologic characteristics, treatment, outcome and prognostic factors.
梭形细胞癌:一般人口统计学、基本临床病理特征、治疗、结局及预后因素
Oncotarget. 2017 Jun 27;8(26):43228-43236. doi: 10.18632/oncotarget.18017.
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Spindle Cell Sarcomas.梭形细胞肉瘤
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Clinical manifestations and radiological features may contribute to the early diagnosis of radiation-induced sarcoma after breast cancer.临床表现和放射学特征可能有助于乳腺癌放疗后放射性肉瘤的早期诊断。
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Breast Cancer Res. 2014;16(2):205. doi: 10.1186/bcr3630.
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WHO classification of soft tissue tumours: an update based on the 2013 (4th) edition.世界卫生组织软组织肿瘤分类:基于 2013 年(第 4 版)的更新。
Pathology. 2014 Feb;46(2):95-104. doi: 10.1097/PAT.0000000000000050.
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Latest biopsy approach for suspected metastases in patients with breast cancer.乳腺癌疑似转移患者的最新活检方法。
Nat Rev Clin Oncol. 2013 Dec;10(12):711-9. doi: 10.1038/nrclinonc.2013.182. Epub 2013 Oct 22.
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Treatment of estrogen receptor-positive breast cancer.雌激素受体阳性乳腺癌的治疗。
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