Fujita Takeshi, Kobayashi Takaaki, Saito Kazuya, Seo Toru, Ikezono Tetsuo, Doi Katsumi
Department of Otolaryngology, Kindai University Faculty of Medicine, Osaka, Japan.
Department of Otolaryngology, Saitama Medical University, Saitama, Japan.
Front Neurol. 2019 Jan 30;10:47. doi: 10.3389/fneur.2019.00047. eCollection 2019.
An 8-year-old boy was referred to the ENT department for further evaluation of right-sided conductive hearing loss. A small cyst anterior to the oval window and fixation of the stapes footplate were observed during an exploratory tympanotomy. The concentration of a perilymph-specific protein, cochlin-tomoprotein (CTP), in the middle ear lavage fluid was measured with an ELISA-based CTP detection kit. The level of CTP in the middle ear lavage fluid before fenestration of the cyst was 0.26 ng/ml (negative), and its level after fenestration was 2.98 ng/ml (positive), confirming the presence of perilymph in the cyst. A small bone dehiscence, considered to be the fissula ante fenestram, was observed anterior to the stapes footplate after removal of the cyst. The CTP detection test results allowed us to confirm that the small bone dehiscence was connected to the inner ear.
一名8岁男孩因右侧传导性听力损失被转诊至耳鼻喉科进行进一步评估。在探查性鼓室切开术中，观察到卵圆窗前方有一个小囊肿，镫骨底板固定。使用基于酶联免疫吸附测定（ELISA）的耳蜗蛋白-托莫蛋白（CTP）检测试剂盒测量中耳灌洗液中一种外淋巴特异性蛋白CTP的浓度。囊肿开窗术前中耳灌洗液中CTP水平为0.26 ng/ml（阴性），开窗术后为2.98 ng/ml（阳性），证实囊肿内存在外淋巴。在囊肿切除后，在镫骨底板前方观察到一个小的骨质缺损，被认为是窗前裂。CTP检测结果使我们能够确认这个小的骨质缺损与内耳相连。
