Harper Kristie J, Riley Vera, Jacques Angela, MacDonald Kirsty, Spendier Nicholas
Occupational Therapy, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Department of Rehabilitation and Aged Care, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Australas J Ageing. 2019 Sep;38(3):199-205. doi: 10.1111/ajag.12629. Epub 2019 Feb 14.
To assess the ability of the Australian Modified Lawton's Instrumental Activities of Daily Living (IADL) Scale (Modified Lawton's Scale) to screen for cognitive impairment in patients without physical or sensory deficits.
Prospective single-blind study of diagnostic accuracy.
Data were available for 249 patients. At ≤25 points on the Modified Lawton's Scale, the area under the receiver operating characteristic curve (AUC) for patients with dementia was 0.90 (95% CI 0.83, 0.96), with sensitivity of 95% and specificity of 84%. The scale had decreased ability to identify patients with mild cognitive impairment (MCI) with the AUC highest at 0.76 (95% CI 0.67, 0.84), with a sensitivity of 77% and specificity of 74% at ≤26 points. The Modified Lawton's Scale had a significant strong correlation with the Mini-Mental State Examination (0.73) (P ≤ 0.001).
A score of ≤25 on the Modified Lawton's Scale may indicate cognitive impairment impacting on IADL.
评估澳大利亚修订版劳顿日常生活能力量表(修订版劳顿量表)对无身体或感官缺陷患者认知障碍的筛查能力。
对诊断准确性进行前瞻性单盲研究。
有249例患者的数据可用。在修订版劳顿量表得分≤25分时,痴呆患者的受试者工作特征曲线下面积(AUC)为0.90(95%可信区间0.83,0.96),敏感性为95%,特异性为84%。该量表识别轻度认知障碍(MCI)患者的能力下降,在得分≤26分时AUC最高为0.76(95%可信区间0.67,0.84),敏感性为77%,特异性为74%。修订版劳顿量表与简易精神状态检查表有显著强相关性(0.73)(P≤0.001)。
修订版劳顿量表得分≤25分可能表明认知障碍影响日常生活能力。