评估心脏移植患者的心肌复极离散度。
Evaluation of myocardial dispersion of repolarization in patients with heart transplantation.
出版信息
Turk J Med Sci. 2019 Feb 11;49(1):212-216. doi: 10.3906/sag-1807-90.
BACKGROUND/AIM: The number of patients with heart transplantation has dramatically increased in the last decade. Considerable studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarization and increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. We analyzed the dispersion of myocardial repolarization using electrocardiographic Tp-e interval and Tp-e/QTc ratio in patients with heart transplantation.
MATERIALS AND METHODS
This observational study included 38 patients (12 female and 26 male) with heart transplantation and 38 well-matched controls. From electrocardiograms, Tp-e interval and Tp-e/QTc ratio were calculated and compared between the 2 groups.
RESULTS
Noninvasive arrhythmia indicators including Tp-e interval (84.63 ± 14.17 ms vs 71.82 ± 7.47 ms, P < 0.001), Tp-e/QTc ratio (0.19 ± 0.04 vs 0.16 ± 0.02, P < 0.001) and QTc interval except QT interval were significantly higher in transplanted hearts compared to normal hearts.
CONCLUSION
Patients with heart transplantation have increased myocardial dispersion of repolarization.
背景/目的：在过去的十年中，接受心脏移植的患者数量显著增加。大量研究表明，心电图 T 波峰至终点（Tp-e）的时间间隔可能与复极跨壁离散度相对应，Tp-e 间期和 Tp-e/QT 比值的增加与恶性室性心律失常相关。我们分析了心脏移植患者的心电图 Tp-e 间期和 Tp-e/QTc 比值的心肌复极离散度。
材料和方法
本观察性研究纳入了 38 例（女性 12 例，男性 26 例）心脏移植患者和 38 例匹配良好的对照组。从心电图计算 Tp-e 间期和 Tp-e/QTc 比值，并比较两组之间的差异。
结果
与正常心脏相比，移植心脏的非侵入性心律失常指标 Tp-e 间期（84.63 ± 14.17 ms 比 71.82 ± 7.47 ms，P < 0.001）、Tp-e/QTc 比值（0.19 ± 0.04 比 0.16 ± 0.02，P < 0.001）和 QTc 间期（QT 间期除外）明显升高。
结论
心脏移植患者的心肌复极离散度增加。
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