Institute of Immunomorphology, Centre of Anatomy, Medical School Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Cell Tissue Res. 2019 Apr;376(1):19-24. doi: 10.1007/s00441-019-02994-z. Epub 2019 Feb 14.
The thymus is a primary lymphoid organ where T lymphocyte proliferation and selection takes place. The different subsets of lymphocytes leave the thymus as recent thymic emigrants. Peripheral dendritic cells migrate to the thymus. In addition to the homing of hematopoietic progenitor cells to the thymus, there is evidence for lymphocyte entry from peripheral lymphoid tissues mainly into the medulla. The entry sites are the venules in the medullary part near to the cortex with a higher endothelium. Furthermore, there are also B lymphocytes in the thymus. The thymus is not only a primary lymphoid organ but is well integrated in lymphocyte traffic as shown in several different species.
胸腺是 T 淋巴细胞增殖和选择发生的主要淋巴器官。不同亚群的淋巴细胞作为近期胸腺移居者离开胸腺。外周树突状细胞迁移到胸腺。除了造血祖细胞归巢到胸腺外，还有证据表明淋巴细胞主要从外周淋巴组织进入髓质。进入部位是靠近皮质的髓质部分的小静脉，内皮较高。此外，胸腺中也存在 B 淋巴细胞。胸腺不仅是一个主要的淋巴器官，而且在淋巴细胞运输中也很好地整合在一起，这在几个不同的物种中都有显示。
