Ali Mohammed, Ali Mujtaba, Mohamed Ahmed, Mannan Syed, Fallahi Farshid
North Cumbria University Hospital NHS Trust , Carlisle , United Kingdom.
Health Education North East , Newcastle upon Tyne , United Kingdom.
J Ultrason. 2018;18(75):325-331. doi: 10.15557/JoU.2018.0047.
Ultrasonography is widely utilized by emergency physicians and radiologists to diagnose various orthopaedic diseases, including fractures. We aim to derive a definitive estimate of the diagnostic accuracy of ultrasonography in clinically suspected scaphoid fractures. We undertook a systematic review and meta-analysis of included diagnostic cohort studies that discussed the use of ultrasonography in the diagnosis of occult scaphoid fractures. We searched the National Institute for Health and Care Excellence database using the Healthcare Databases Advanced Search tool. In addition, we utilized the PubMed database to search the Medical Literature Analysis and Retrieval System Online, Excerpta Medica database, Cumulative Index of Nursing and Allied Health and Allied and Complimentary Medicine databases. Studies were included if they discuss the role of ultrasound imaging in the diagnosis of scaphoid fractures based on cortical interruption, radio-carpal effusion and scapho-trapezium-trapezoid effusion. Quality assessment was performed using the methodological index for non-randomized studies scoring system. 6 non-randomized control studies met the inclusion criteria. Collectively, these included 236 patients with a mean age ranging from 18 to 41.2 years. The quality of these articles ranged between moderate and high based on the methodological index for non-randomized studies score. The mean sensitivity was 88.95% (standard deviation 10.03) and mean specificity was 89.50% (standard deviation 12.21). The current literature reveals high sensitivity and specificity in the use of ultrasonography in scaphoid fracture diagnosis. However, multiple factors including technical differences in ultrasound machines and probes, small sample sizes and variability of subsequent confirmatory tests have created a challenge in determining the ultimate reliability of ultrasonography in the diagnosis of occult scaphoid fractures. Considering these factors and limitations, large-sample and high-quality clinical trials are needed to adequately assess its reliability for this purpose. One stop clinics, in the authors' opinion, would be an ideal setting for its introduction as well as for future trials. Ultrasonography is widely utilized by emergency physicians and radiologists to diagnose various orthopaedic diseases, including fractures. We aim to derive a definitive estimate of the diagnostic accuracy of ultrasonography in clinically suspected scaphoid fractures. We undertook a systematic review and meta-analysis of included diagnostic cohort studies that discussed the use of ultrasonography in the diagnosis of occult scaphoid fractures. We searched the National Institute for Health and Care Excellence database using the Healthcare Databases Advanced Search tool. In addition, we utilized the PubMed database to search the Medical Literature Analysis and Retrieval System Online, Excerpta Medica database, Cumulative Index of Nursing and Allied Health and Allied and Complimentary Medicine databases. Studies were included if they discuss the role of ultrasound imaging in the diagnosis of scaphoid fractures based on cortical interruption, radio-carpal effusion and scapho-trapezium-trapezoid effusion. Quality assessment was performed using the methodological index for non-randomized studies scoring system. 6 non-randomized control studies met the inclusion criteria. Collectively, these included 236 patients with a mean age ranging from 18 to 41.2 years. The quality of these articles ranged between moderate and high based on the methodological index for non-randomized studies score. The mean sensitivity was 88.95% (standard deviation 10.03) and mean specificity was 89.50% (standard deviation 12.21). The current literature reveals high sensitivity and specificity in the use of ultrasonography in scaphoid fracture diagnosis. However, multiple factors including technical differences in ultrasound machines and probes, small sample sizes and variability of subsequent confirmatory tests have created a challenge in determining the ultimate reliability of ultrasonography in the diagnosis of occult scaphoid fractures. Considering these factors and limitations, large-sample and high-quality clinical trials are needed to adequately assess its reliability for this purpose. One stop clinics, in the authors’ opinion, would be an ideal setting for its introduction as well as for future trials.
超声检查被急诊医生和放射科医生广泛用于诊断包括骨折在内的各种骨科疾病。我们旨在对超声检查在临床疑似舟状骨骨折中的诊断准确性得出一个确切的估计。我们对纳入的诊断队列研究进行了系统评价和荟萃分析,这些研究讨论了超声检查在隐匿性舟状骨骨折诊断中的应用。我们使用医疗数据库高级搜索工具搜索了英国国家卫生与临床优化研究所数据库。此外,我们利用PubMed数据库搜索了医学文献分析与联机检索系统、医学文摘数据库、护理及相关健康累积索引以及补充医学数据库。如果研究讨论了基于皮质中断、桡腕关节积液和舟月三角关节积液的超声成像在舟状骨骨折诊断中的作用,则纳入该研究。使用非随机研究评分系统的方法学指标进行质量评估。6项非随机对照研究符合纳入标准。这些研究总共纳入了236例患者,平均年龄在18至41.2岁之间。根据非随机研究评分系统的方法学指标,这些文章的质量在中等至高等之间。平均敏感性为88.95%(标准差10.03),平均特异性为89.50%(标准差12.21)。当前文献表明,超声检查在舟状骨骨折诊断中的应用具有较高的敏感性和特异性。然而,包括超声机器和探头的技术差异、样本量小以及后续确诊试验的变异性等多种因素,给确定超声检查在隐匿性舟状骨骨折诊断中的最终可靠性带来了挑战。考虑到这些因素和局限性,需要进行大样本和高质量的临床试验,以充分评估其在这方面的可靠性。作者认为,一站式诊所将是引入超声检查以及进行未来试验的理想场所。超声检查被急诊医生和放射科医生广泛用于诊断包括骨折在内的各种骨科疾病。我们旨在对超声检查在临床疑似舟状骨骨折中的诊断准确性得出一个确切的估计。我们对纳入的诊断队列研究进行了系统评价和荟萃分析,这些研究讨论了超声检查在隐匿性舟状骨骨折诊断中的应用。我们使用医疗数据库高级搜索工具搜索了英国国家卫生与临床优化研究所数据库。此外,我们利用PubMed数据库搜索了医学文献分析与联机检索系统、医学文摘数据库、护理及相关健康累积索引以及补充医学数据库。如果研究讨论了基于皮质中断、桡腕关节积液和舟月三角关节积液的超声成像在舟状骨骨折诊断中的作用,则纳入该研究。使用非随机研究评分系统的方法学指标进行质量评估。6项非随机对照研究符合纳入标准。这些研究总共纳入了236例患者,平均年龄在18至41.2岁之间。根据非随机研究评分系统的方法学指标,这些文章的质量在中等至高等之间。平均敏感性为88.95%(标准差10.03),平均特异性为89.50%(标准差12.21)。当前文献表明,超声检查在舟状骨骨折诊断中的应用具有较高的敏感性和特异性。然而,包括超声机器和探头的技术差异、样本量小以及后续确诊试验的变异性等多种因素,给确定超声检查在隐匿性舟状骨骨折诊断中的最终可靠性带来了挑战。考虑到这些因素和局限性,需要进行大样本和高质量的临床试验,以充分评估其在这方面的可靠性。作者认为,一站式诊所将是引入超声检查以及进行未来试验的理想场所。