Gallitto Enrico, Faggioli Gianluca, Pini Rodolfo, Mascoli Chiara, Freyrie Antonio, Vento Vincenzo, Ancetti Stefano, Stella Andrea, Gargiulo Mauro
Vascular Surgery, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Policlinico Sant'Orsola-Malpighi, Bologna, Italy.
Vascular Surgery, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Policlinico Sant'Orsola-Malpighi, Bologna, Italy.
Ann Vasc Surg. 2019 Jul;58:211-221. doi: 10.1016/j.avsg.2018.12.065. Epub 2019 Feb 11.
To report perioperative and 1-year results of total endovascular repair of contained ruptured thoracoabdominal aortic aneurysms (TAAAs).
Between 2015 and 2017, preoperative, procedural, and postoperative data of patients with radiographic evidence of contained ruptured TAAAs treated by endovascular repair were prospectively collected. Only patients with stable hemodynamic parameters were enclosed. Primary endpoints were 30-day/in-hospital mortality, spinal cord ischemia (SCI), postoperative cardiopulmonary complications, and new onset of hemodialysis. Secondary endpoints were endoleaks, reinterventions, and overall follow-up survival.
Twelve patients underwent endovascular repair for contained ruptured TAAAs. According with the Crawford/Safi's classification, 6 type II (50%), 3 type III (25%), 1 type IV (8%), and 2 type V (17%) TAAAs were treated. All patients were symptomatic. Overall, 34 target visceral vessels were planned to be revascularized. The mean time from admission to treatment was 48 hours (range 4-96), with 4 patients operated within 24 hours. Five patients (42%) were treated by T-branch, 3 (25%) by custom-made fenestrated/branched endografts, 3 (25%) by parallel graft technique, and 1 (8%) by standard thoracic endovascular aortic repair covering a stenotic celiac trunk. The 30-day and in-hospital mortality was 17% and 25%, respectively. Two patients (17%) developed SCI. Cardiac and pulmonary complications were reported in 1 (8%) and 3 (25%) cases, respectively. One patient (8%) needed permanent hemodialysis. Two endoleaks (17%) were detected at the postoperative computed tomography angiography (1 low-flow gutter endoleak and 1 type III endoleak). Four patients (33%) required re-interventions within 30 postoperative days. The mean follow-up was 12 months (range 1-22). No late target visceral vessels occlusion, endoleak, or reintervention occurred in this series. Overall, 7/12 (59%) patients were alive, and no cases of TAAA-related mortality occurred during follow-up.
According to our results, endovascular repair of contained ruptured TAAAs is feasible by a flexible approach in selected patients with anatomical suitability and stable hemodynamic conditions. Although early mortality and morbidity are significant, with frequent reintervention necessity, subsequent follow-up is free from reinterventions and TAAA-related mortality.
报告腔内修复局限性破裂胸腹主动脉瘤(TAAA)的围手术期及1年结果。
2015年至2017年,前瞻性收集经腔内修复治疗的有影像学证据的局限性破裂TAAA患者的术前、手术过程及术后数据。仅纳入血流动力学参数稳定的患者。主要终点为30天/住院死亡率、脊髓缺血(SCI)、术后心肺并发症及新发血液透析。次要终点为内漏、再次干预及总体随访生存率。
12例患者接受了局限性破裂TAAA的腔内修复。根据Crawford/Safi分类,治疗了6例II型(50%)、3例III型(25%)、1例IV型(8%)及2例V型(17%)TAAA。所有患者均有症状。总体而言,计划对34支目标内脏血管进行血运重建。从入院到治疗的平均时间为48小时(范围4 - 96小时),4例患者在24小时内接受手术。5例患者(42%)采用T型分支治疗,3例(25%)采用定制开窗/分支型腔内移植物治疗,3例(25%)采用平行移植物技术治疗,1例(8%)采用覆盖狭窄腹腔干的标准胸主动脉腔内修复术治疗。30天及住院死亡率分别为17%和25%。2例患者(17%)发生SCI。分别有1例(8%)和3例(25%)报告了心脏和肺部并发症。1例患者(8%)需要永久性血液透析。术后计算机断层扫描血管造影检测到2例内漏(17%)(1例低流量沟内漏和1例III型内漏)。4例患者(33%)在术后30天内需要再次干预。平均随访时间为12个月(范围1 - 22个月)。本系列中未发生晚期目标内脏血管闭塞、内漏或再次干预。总体而言,7/12(59%)例患者存活,随访期间未发生与TAAA相关的死亡病例。
根据我们的结果,对于具有解剖学适宜性和血流动力学稳定条件的选定患者,采用灵活的方法对局限性破裂TAAA进行腔内修复是可行的。尽管早期死亡率和发病率较高,且经常需要再次干预,但随后的随访未发生再次干预及与TAAA相关的死亡。