Department of Chemical Engineering, National Cheng Kung University, No. 1, University Rd., Tainan 70101, Taiwan.
Department of Chemical Engineering, National Cheng Kung University, No. 1, University Rd., Tainan 70101, Taiwan; Hierarchical Green-Energy Materials (Hi-GEM) Research Center, National Cheng Kung University, Tainan 70101, Taiwan.
J Colloid Interface Sci. 2019 Apr 15;542:243-252. doi: 10.1016/j.jcis.2019.02.014. Epub 2019 Feb 6.
Biomimetic synthesis of silica/polymer hybrid nanomaterials inspired by silica-condensing microorganisms has gained significant advances in recent years and the as-prepared hybrid materials have been explored for a variety of applications. In this work, silica/polypeptide hybrid nanoparticles (NPs) and coating films can be facilely fabricated by silica mineralization of poly(l-lysine)-block-poly(l-threonine)/poly(l-glutamic acid) (PLL-b-PLT/PGA) fibril complexes assembled in solutions or on substrates at benign conditions. The experimental data revealed that PLL-b-PLT can self-assemble to form fibrils via intermolecular hydrogen bonding interactions between PLT chains and, upon complexing with PGA, silicas were efficiently mineralized in both the sheet-like PLL/PGA complexes and PLT domains, resulting in the fabrication of silica/polypeptide hybrid materials. After removing the polypeptides, mesoporous silicas exhibiting pore size between 2 and 10 nm and large pores (>10 nm) were fabricated by the replication of the sheet-like polypeptides and fibril complexes/aggregates, respectively. This study demonstrates that these polypeptide fibril complexes can serve both as nucleating agents and as templates for the fabrication of oxide/polypeptide hybrid NPs, mesoporous oxides and oxide/polypeptide coating films, which have potential applications in a variety of areas.
受硅质凝结微生物启发的仿生合成二氧化硅/聚合物杂化纳米材料近年来取得了重大进展，所制备的杂化材料已被探索用于各种应用。在这项工作中，通过在温和条件下在溶液中或在基底上组装的聚（L-赖氨酸）-嵌段-聚（L-苏氨酸）/聚（L-谷氨酸）（PLL-b-PLT/PGA）纤维复合物的二氧化硅矿化，可以容易地制备二氧化硅/多肽杂化纳米颗粒（NPs）和涂层膜。实验数据表明，PLL-b-PLT 可以通过 PLT 链之间的分子间氢键相互作用自组装形成纤维，并且在与 PGA 络合后，硅可以在片状 PLL/PGA 复合物和 PLT 结构域中有效地矿化，从而制备出二氧化硅/多肽杂化材料。在去除多肽后，通过片状多肽和纤维复合物/聚集体的复制，分别制造了具有 2-10nm 之间的孔径和大孔（>10nm）的介孔硅。这项研究表明，这些多肽纤维复合物可以用作核化剂和氧化物/多肽杂化 NPs、介孔氧化物和氧化物/多肽涂层膜的模板，它们在各种领域都有潜在的应用。
