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男性肥胖与生育能力下降

Obesity and reduced fertility of men.

作者信息

Škurla M, Rybář R

出版信息

Ceska Gynekol. 2018 Winter;83(3):212-217.

PMID:30764622
Abstract

OBJECTIVE

Description of the relationship between the overweight man and the reduction of his reproductive potential.

DESIGN

Review article.

SETTING

Center of Assisted Reproduction Sanus, Jihlava.

METHODS

Approximately 15% of couples are trying to get pregnant unsuccessfully. In order to better assess the possible causes of this failure, it is vital to take into consideration the influence of owerweight and/or obesity in both men and women. Reduction of the reproductive potential of obese men occurs due to changes in hormonal levels regulating spermatogenesis, increased temperatures in the testicles, environmental toxins accumulated in adipose tissue, increased levels of oxidative stress as well as a higher incidence of erectile dysfunction. The likelihood of pregnancy is reduced even in the case of assisted reproduction methods.

CONCLUSION

Obesity or overweight causes reduced fertility of men and often significantly prolongs the time required to achieve pregnancy. Prior to applying treatment for infertility, we assess all possibilities to increase the reproductive potential of overweight men. Significant weight loss in obese men results in regulated hormonal levels, moreover, in most cases, this leads to improved spermiogram parameters with increasing chances of getting pregnant.

摘要

目的

描述超重男性与其生殖潜能降低之间的关系。

设计

综述文章。

地点

伊赫拉瓦Sanus辅助生殖中心。

方法

约15%的夫妇试图怀孕但未成功。为了更好地评估这种失败的可能原因,考虑超重和/或肥胖对男性和女性的影响至关重要。肥胖男性生殖潜能的降低是由于调节精子发生的激素水平变化、睾丸温度升高、脂肪组织中积累的环境毒素、氧化应激水平升高以及勃起功能障碍的发生率较高。即使采用辅助生殖方法,怀孕的可能性也会降低。

结论

肥胖或超重会导致男性生育能力下降,并常常显著延长怀孕所需时间。在应用不孕症治疗之前,我们会评估所有提高超重男性生殖潜能的可能性。肥胖男性显著减重会使激素水平得到调节,此外,在大多数情况下,这会导致精液参数改善,怀孕几率增加。

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