免疫缺陷小鼠因饮用水被……污染而出现头部倾斜。 （你提供的原文似乎不完整，“by”后面缺少具体内容）
Head Tilt in Immunodeficient Mice Due to Contamination of Drinking Water by .
作者信息
Collymore Chereen, Giuliano Frank, Banks E Kate
机构信息
Division of Comparative Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Animal Care and Veterinary Services, University of Ottawa, Ottawa, Ontario, Canada.
Division of Comparative Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
出版信息
J Am Assoc Lab Anim Sci. 2019 Mar 1;58(2):246-250. doi: 10.30802/AALAS-JAALAS-18-000106. Epub 2019 Feb 14.
Abstract
Immunodeficient mice in multiple holding rooms presented with head tilt, circling, spinning when picked up by the tail, dehydration, and lethargy. , a plant pathogen, was identified as the causative agent. Environmental testing revealed the presence of within the automatic watering system, water bottles, and sipper tubes. Here we describe steps taken to reduce the presence of this organism within the automatic watering system and water bottles. Facilities housing immunodeficient mice should take measures to minimize the accumulation of biofilm within their water-supply systems.
摘要
多个饲养室中的免疫缺陷小鼠出现了头部倾斜、转圈、被尾巴拎起时旋转、脱水和嗜睡的症状。一种植物病原体被确定为病原体。环境检测发现自动浇水系统、水瓶和吸管中存在该病原体。在此我们描述了为减少自动浇水系统和水瓶中这种生物体的存在而采取的措施。饲养免疫缺陷小鼠的设施应采取措施，尽量减少其供水系统中生物膜的积累。
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本文引用的文献
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Can Respir J. 2011 Jul-Aug;18(4):e64-5. doi: 10.1155/2011/304179.
4
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