囊性纤维化中微生物流行病学的变化。
The changing microbial epidemiology in cystic fibrosis.
机构信息
Department of Pediatrics and Communicable Diseases, 1150 W. Medical Center Drive, 8323 MSRB III, SPC 5646, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
出版信息
Clin Microbiol Rev. 2010 Apr;23(2):299-323. doi: 10.1128/CMR.00068-09.
Abstract
Infection of the airways remains the primary cause of morbidity and mortality in persons with cystic fibrosis (CF). This review describes salient features of the epidemiologies of microbial species that are involved in respiratory tract infection in CF. The apparently expanding spectrum of species causing infection in CF and recent changes in the incidences and prevalences of infection due to specific bacterial, fungal, and viral species are described. The challenges inherent in tracking and interpreting rates of infection in this patient population are discussed.
摘要
气道感染仍然是囊性纤维化（CF）患者发病率和死亡率的主要原因。本综述描述了与 CF 患者呼吸道感染有关的微生物物种的流行病学的显著特征。描述了引起 CF 感染的物种范围明显扩大，以及特定细菌、真菌和病毒物种感染的发生率和流行率的近期变化。讨论了在该患者人群中跟踪和解释感染率所固有的挑战。
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