Kuang Weicong, Zhong Qing, Ye Xiaoli, Yan Yayuan, Yang Yunhua, Zhang Jingxian, Huang Langhuan, Tan Shaozao, Shi Qingshan
Guangdong Engineering and Technology R&D Center of Graphene or Its Like Materials and Products, Department of Chemistry, Jinan University, Guangzhou, Guangdong 510632, China.
School of Chemistry and Chemical Engineering, Guangzhou University, 510006, China.
J Nanosci Nanotechnol. 2019 Jul 1;19(7):3982-3990. doi: 10.1166/jnn.2019.16320.
Due to secondary pollution from bactericidal substances, the importance of eliminating microbial contamination has become a controversial topic. Three antibacterial nanorod materials of carbon quantum dots-zinc oxide (1/3CQDs-ZnO, CQDs-ZnO, and 2CQDs-ZnO), in which ZnO nanorods are surrounded by carbon quantum dots (CQDs), were successful prepared via sol-gel chemistry. Antibacterial nanorods of CQDs-ZnO had strong antibacterial activity under visible light irradiation, and a concentration of 0.1 mg/L was able to kill more than 96% of bacteria. The photocatalytic antibacterial mechanism was also studied. CQDs-ZnO produced more than three times the free radicals than pure ZnO under visible light irradiation. These free radicals destroyed the bacterial matrix of the cell wall and released cell proteins and nucleic acids. Moreover, CQDs-ZnO showed low cytotoxicity and can be used in medical applications.
由于杀菌物质的二次污染，消除微生物污染的重要性已成为一个有争议的话题。通过溶胶 - 凝胶化学成功制备了三种碳量子点 - 氧化锌抗菌纳米棒材料（1/3CQDs - ZnO、CQDs - ZnO和2CQDs - ZnO），其中氧化锌纳米棒被碳量子点（CQDs）包围。CQDs - ZnO抗菌纳米棒在可见光照射下具有很强的抗菌活性，浓度为0.1 mg/L时能够杀灭超过96%的细菌。还研究了光催化抗菌机制。在可见光照射下，CQDs - ZnO产生的自由基比纯氧化锌多三倍以上。这些自由基破坏了细胞壁的细菌基质，释放出细胞蛋白质和核酸。此外，CQDs - ZnO表现出低细胞毒性，可用于医学应用。
