Yawn Robert J, Nassiri Ashley M, Rivas Alejandro
The Otology Group of Vanderbilt, Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, 7209 Medical Center East, South Tower 1215 21st Avenue South, Nashville, TN 37232-8605, USA.
The Otology Group of Vanderbilt, Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, 7209 Medical Center East, South Tower 1215 21st Avenue South, Nashville, TN 37232-8605, USA.
Otolaryngol Clin North Am. 2019 Apr;52(2):349-355. doi: 10.1016/j.otc.2018.11.016. Epub 2019 Feb 12.
Auditory neuropathy spectrum disorder (ANSD) is a complex and heterogeneous disorder associated with altered neural synchrony with respect to auditory stimuli. Patients have characteristic auditory findings including normal otoacoustic emissions in the setting of abnormal auditory brainstem response. Patients with ANSD have a high incidence of comorbid developmental delay that may impact speech outcomes. Treatment options for ANSD include hearing amplification and cochlear implantation. The article highlights issues and controversies with the diagnosis and treatment of this complex disorder.
听觉神经病谱系障碍（ANSD）是一种复杂的异质性疾病，与听觉刺激相关的神经同步性改变有关。患者具有特征性的听觉表现，包括在听觉脑干反应异常的情况下耳声发射正常。ANSD患者合并发育迟缓的发生率较高，这可能会影响言语发育结果。ANSD的治疗选择包括听力放大和人工耳蜗植入。本文重点介绍了这种复杂疾病诊断和治疗中存在的问题及争议。
