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剖宫产术中麦角新碱诱发的心房颤动。

Ergometrine-induced atrial fibrillation at caesarean section.

作者信息

Birch Samuel, Lu Corrine

机构信息

Cardiology department, St Vincent's Hospital, Darlinghurst, New South Wales, Australia.

Department of Obstetrics and Gynaecology, Centenary Hospital for Women and Children, Canberra Hospital, Garran, Australian Capital Territory, Australia.

出版信息

BMJ Case Rep. 2019 Feb 13;12(2):e226747. doi: 10.1136/bcr-2018-226747.

DOI:10.1136/bcr-2018-226747
PMID:30765440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6381988/
Abstract

A 36-year-old woman with a history of one previous caesarean section presented to the birthing suite of a regional hospital with spontaneous rupture of membranes at 39+2/40 weeks. Syntocinon was administered to initiate uterine contractions in the absence of labour, as the patient desired vaginal birth. A caesarean section was subsequently indicated and ergometrine was administered for uterine atony. The patient immediately developed atrial fibrillation (AF). AF is the most common sustained arrhythmia in the general population, but is rare in the obstetric population. AF occurring in an intrapartum setting following the administration of syntocinon and ergometrine, is not documented in the literature. We suggest the initiation of paroxysmal AF was precipitated by an abrupt alteration in autonomic tone caused by administration of syntocinon followed by ergometrine.

摘要

一名有过一次剖宫产史的36岁女性,在孕39⁺²/40周时胎膜自然破裂,被送往一家地区医院的分娩室。由于患者希望顺产,在未临产的情况下使用了缩宫素以启动子宫收缩。随后决定进行剖宫产,并使用麦角新碱治疗宫缩乏力。患者随即出现房颤(AF)。房颤是普通人群中最常见的持续性心律失常,但在产科人群中很少见。文献中未记载在使用缩宫素和麦角新碱后产时发生房颤的情况。我们认为,阵发性房颤的发作是由先使用缩宫素后使用麦角新碱导致自主神经张力突然改变所诱发的。

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本文引用的文献

1
Cardiac Arrhythmias and Pregnancy.心律失常与妊娠
Curr Treat Options Cardiovasc Med. 2018 Jul 11;20(8):63. doi: 10.1007/s11936-018-0660-9.
2
Prevalence and treatment of atrial fibrillation in UK general practice from 2000 to 2016.2000 年至 2016 年英国普通实践中房颤的患病率和治疗情况。
Heart. 2019 Jan;105(1):27-33. doi: 10.1136/heartjnl-2018-312977. Epub 2018 Jul 10.
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Ventricular tachycardia observed during cesarean section in a patient without structural cardiac disease.在剖宫产过程中,一名无结构性心脏病的患者出现室性心动过速。
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Burden of Arrhythmia in Pregnancy.妊娠期心律失常的负担
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Atrial Fibrillation: Pathophysiology and Therapeutic Options.心房颤动:病理生理学与治疗选择
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Dysfunction of the autonomic nervous system in atrial fibrillation.心房颤动中自主神经系统的功能障碍。
J Thorac Dis. 2015 Feb;7(2):193-8. doi: 10.3978/j.issn.2072-1439.2015.01.12.
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Oxytocin does not directly alter cardiac repolarization in rabbit or human cardiac myocytes.催产素不会直接改变兔或人心肌细胞的心脏复极化。
Pharmacol Res Perspect. 2015 Feb;3(1):e00102. doi: 10.1002/prp2.102. Epub 2014 Dec 9.
10
Estimating the current and future prevalence of atrial fibrillation in the Australian adult population.估算澳大利亚成年人群中心房颤动的当前和未来患病率。
Med J Aust. 2015 Jan 19;202(1):32-5. doi: 10.5694/mja14.00238.