SDF1α-induced chemotaxis of JAK2-V617F-positive cells is dependent on Bruton tyrosine kinase and its downstream targets PI3K/AKT, PLCγ1 and RhoA.
作者信息
Nimmagadda Subbaiah Chary, Frey Stephanie, Müller Peter, Wolleschak Denise, Weinert Sönke, Keller Ulrich, Edelmann Bärbel, Fischer Thomas
机构信息
Department of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg.
Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke-University, Magdeburg.
出版信息
Haematologica. 2019 Jul;104(7):e288-e292. doi: 10.3324/haematol.2018.201921. Epub 2019 Feb 14.
Abstract
摘要
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