University of California San Diego.
Blood. 2019 Feb 14;133(7):631-632. doi: 10.1182/blood-2018-12-891515.
In this issue of , Zheng et al provide insight into the source of intravascular tissue–type plasminogen activator (tPA). They demonstrate an important role for hepatocytes in determining the basal level of plasma tPA and identify regulatory factors that control tPA expression by hepatocytes.
本期《 》中,郑等人深入探讨了血管内组织型纤溶酶原激活物(tPA)的来源。他们证明了肝细胞在决定血浆 tPA 的基础水平方面起着重要作用,并确定了控制肝细胞中 tPA 表达的调节因子。