Adegoke Oluseyi, Awolola Nicholas Awodele, Ajuluchukwu Jayne Ngozi
College of Medicine, University of Lagos, Nigeria, Department of Medicine.
College of Medicine, University of Lagos, Nigeria, Anatomic and Molecular Pathology Department.
Afr Health Sci. 2018 Dec;18(4):942-949. doi: 10.4314/ahs.v18i4.13.
In developed countries 50% - 75% of deaths from cardiovascular-diseases occurs out-of-hospital. In Nigeria where patronage of orthodox health facilities is low, the impact of cardiovascular-related diseases on out-of-hospital mortality has been sparsely studied.
To determine the prevalence and pattern of cardiovascular-related causes of out-of-hospital deaths in Lagos, Nigeria.
A 5-year retrospective review of all autopsied medical decedents brought-in-dead (BID) to a Nigerian tertiary health facility to identify cardiovascular-related causes of death.
A total of 90 cardiovascular-related deaths out of 176 medical BID cases were identified, giving a prevalence of 51.1%. Mean age was 65.2 ± 15.6 years. Male: Female ratio was 1.4: 1, the females were older (68.29 ± 14.89) vs (61.63 ± 15.55) years. Age group > 60 years accounted for 63.3% of deaths. Commonest primary diseases were hypertensive heart disease (48.9%) and cerebrovascular accident (24.4%). Myocardial infarction occurred in 8.9%. Heart failure, cerebral dysfunction and unspecified circulatory collapse were the causes of death in 54.4%, 23.3% and 14.4% respectively.
Cardiovascular-related diseases are major contributors to out-of-hospital medical deaths occurring chiefly in those >60 years. Hypertensive heart disease and heart failure are the greatest contributors to this cardiovascular-related disease mortality.
在发达国家，50% - 75%的心血管疾病死亡发生在院外。在尼日利亚，人们对正规医疗机构的利用率较低，心血管相关疾病对院外死亡率的影响鲜有研究。
确定尼日利亚拉各斯院外死亡中心血管相关病因的患病率及模式。
对一家尼日利亚三级医疗机构接收的所有已死亡的尸体解剖医学死者进行为期5年的回顾性研究，以确定心血管相关死因。
在176例医学尸体解剖案例中，共识别出90例心血管相关死亡，患病率为51.1%。平均年龄为65.2±15.6岁。男女比例为1.4:1，女性年龄较大（68.29±14.89岁），而男性为（61.63±15.55岁）。60岁以上年龄组占死亡人数的63.3%。最常见的原发性疾病是高血压性心脏病（48.9%）和脑血管意外（24.4%）。心肌梗死发生率为8.9%。心力衰竭、脑功能障碍和未明确的循环衰竭分别是54.4%、23.3%和14.4%的死亡原因。
心血管相关疾病是院外医学死亡的主要原因，主要发生在60岁以上人群中。高血压性心脏病和心力衰竭是导致这种心血管相关疾病死亡的最大因素。
