非洲和亚洲的伤寒结合疫苗介绍。
Introduction of Typhoid Conjugate Vaccines in Africa and Asia.
机构信息
Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore.
Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom.
出版信息
Clin Infect Dis. 2019 Feb 15;68(Suppl 1):S27-S30. doi: 10.1093/cid/ciy878.
Abstract
Typhoid fever continues to be a major public health concern, particularly in many low- and middle-income countries. The current threats of increasing antimicrobial resistance, urbanization, and climate change elevate the urgency for better prevention and control efforts for typhoid fever. In 2017, the results of ground-breaking research on typhoid conjugate vaccines (TCVs), the World Health Organization prequalification of a TCV, and global policy and financing decisions have set the stage for the introduction of TCVs into routine immunization programs in endemic countries. Country-level decision-making and program planning are critical for local uptake and sustainability.
摘要
伤寒仍然是一个主要的公共卫生关注点，特别是在许多低收入和中等收入国家。目前，抗生素耐药性增加、城市化和气候变化的威胁加剧了对伤寒更好的预防和控制工作的紧迫性。2017 年，伤寒结合疫苗（TCV）的开创性研究结果、世界卫生组织对 TCV 的预认证以及全球政策和融资决策为在流行国家将 TCV 纳入常规免疫规划铺平了道路。国家层面的决策和规划对于当地的采用和可持续性至关重要。
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