National Drug and Alcohol Research Centre, University of New South Wales Sydney, NSW, Australia.
School of Psychology, University of Wollongong, NSW, Australia.
Addiction. 2019 Mar;114(3):404-405. doi: 10.1111/add.14556.
Abuse-deterrent formulations (ADFs) of pharmaceutical opioids have limited capacity to reduce extra-medical use and harm; their impact is likely restricted to prevention of specific practices among population sub-groups. This debate highlights the importance of viewing ADFs as one component in a range of public health responses. Greater involvement of invested parties (e.g., prescribers, consumers) and reframing terminology will reduce discrimination and stigma.
药物阿片类药物的滥用阻止配方（ADFs）减少了非医疗使用和伤害的能力有限；它们的影响可能仅限于预防人群亚群中的特定行为。这场辩论强调了将 ADF 视为一系列公共卫生应对措施的一个组成部分的重要性。更多利益相关方（例如，处方者、消费者）的参与和重新调整术语将减少歧视和污名化。
