Department of Integrative Cancer Therapy and Urology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
J Endourol. 2019 Apr;33(4):302-308. doi: 10.1089/end.2018.0898. Epub 2019 Mar 20.
To conduct a prospective randomized trial to evaluate the efficacy of a novel prophylactic procedure for inguinal hernia (IH) after transperitoneal robot-assisted radical prostatectomy (RARP).
The prophylactic procedure for IH after RARP involved the dissection of the peritoneum ∼5 cm outward from internal inguinal ring (IIR), separating the spermatic cord and vessels from the peritoneum. This was randomly performed on one side (left or right).
A total of 148 cases were included, and IH after RARP was observed in 19 (12.8%) cases, with 11 (7.4%) cases in the right side only, 3 (2.0%) in the left side only, and 5 (3.4%) bilaterally. IHs developed in 9 (6.1%) sides that underwent prophylactic procedure and in 15 (10.1%) that did not. Kaplan-Meier curve analysis revealed no significant difference between the preventive and nonpreventive sides (p = 0.197). Based on the observation during laparoscopic hernioplasty, the prophylactic procedure that strengthened the abdominal wall was by adhesion conglutination of the exfoliated peritoneum in the effective side, and IIRs were opened and developed IH in the ineffective sides. Predictive factors for IH after RARP were not found using Cox proportional hazard model.
The preventive procedure for IH used in this study reduced the incidence of IH after RARP, but the difference was not significant.
进行一项前瞻性随机试验,以评估经腹腔机器人辅助前列腺根治性切除术(RARP)后预防腹股沟疝(IH)的新方法的疗效。
RARP 后 IH 的预防程序包括从内环(IIR)向外解剖腹膜约 5cm,将精索和血管与腹膜分离。这在一侧(左侧或右侧)随机进行。
共纳入 148 例患者,其中 19 例(12.8%)发生 RARP 后 IH,右侧 11 例(7.4%),左侧 3 例(2.0%),双侧 5 例(3.4%)。接受预防性手术的 9 侧(6.1%)和未接受预防性手术的 15 侧(10.1%)发生 IH。Kaplan-Meier 曲线分析显示预防侧与非预防侧之间无显著差异(p=0.197)。根据腹腔镜疝修补术期间的观察,强化腹壁的预防性手术是通过有效侧脱落腹膜的粘连凝结实现的,而无效侧的 IIR 开放并发展 IH。Cox 比例风险模型未发现 RARP 后 IH 的预测因素。
本研究中使用的 IH 预防程序降低了 RARP 后 IH 的发生率,但差异无统计学意义。