Ghamdi Abdul Hamid Al
Department of Ophthalmology, Faculty of Medicine, Taif University, Taif, Saudi Arabia.
Curr Diabetes Rev. 2020;16(3):242-247. doi: 10.2174/1573399815666190215120435.
This study was conducted to discuss the clinical value of published Diabetic Retinopathy Progression determinants.
The data for systematic review was collected from the published studies through PubMed and Medline. These studies discussed the clinical predictors of Diabetic Retinopathy (DR) progression. The common keywords used were diabetic Retinopathy, diabetes mellitus, systolic blood pressure, hemoglobin, and albuminuria.
Diabetic Retinopathy is one of the common causes of irreversible visual impairment among adults. Poor glycemic control, systemic hypertension, diabetes duration, dyslipidemia, and microalbuminuria are the major risk factors for the development and progression of diabetic retinopathy. Recently, increased aortic stiffness has been identified as a prognostic marker of diabetic retinopathy and peripheral neuropathy.
Certain groups of diabetic individuals are at higher risk to have progressive diabetic retinopathy and eventually visual impairment. Clinical determinants and predictors are considered as prognostic markers and could help physicians to develop an effective risk-based screening program for this condition.
本研究旨在探讨已发表的糖尿病视网膜病变进展决定因素的临床价值。
通过PubMed和Medline从已发表的研究中收集系统评价的数据。这些研究讨论了糖尿病视网膜病变（DR）进展的临床预测因素。常用关键词为糖尿病视网膜病变、糖尿病、收缩压、血红蛋白和蛋白尿。
糖尿病视网膜病变是成人不可逆视力损害的常见原因之一。血糖控制不佳、系统性高血压、糖尿病病程、血脂异常和微量白蛋白尿是糖尿病视网膜病变发生和进展的主要危险因素。最近，主动脉僵硬度增加已被确定为糖尿病视网膜病变和周围神经病变的预后标志物。
某些糖尿病患者群体发生进行性糖尿病视网膜病变并最终导致视力损害的风险较高。临床决定因素和预测因素被视为预后标志物，有助于医生制定针对这种情况的有效的基于风险的筛查方案。
