Sierra-Díaz Erick, Hernández-Ríos Cesar J, Bravo-Cuellar Alejandro
Departamento de Urología, UMAE Hospital de Especialidades Centro Medico Nacional de Occidente. Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
Departamento de Inmunología, Centro de Investigación Biomédica de Occidente. Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
Cir Cir. 2019;87(2):176-182. doi: 10.24875/CIRU.18000494.
The objective of this study was to describe the prevalence, microbiological profile, bacterial resistance, and the sensitivity to antibiotics of microorganisms causing urinary tract infection (UTI) at a single-site tertiary referral hospital in the western region of Mexico.
A total of 5895 culture samples processed at the microbiology laboratory from August 1, 2014, to July 31, 2015, were analyzed.
A total of 5895 samples for urine cultures (UC) were collected, of which 3363 were taken in women (57.05%) and 2532 in men (42.95%). A prevalence of 24% was calculated. From 1444 positive UC, 1512 microorganisms were isolated; the major etiological agent was Escherichia coli, representing 67.28% followed by Pseudomonas with 7.12%. With respect to fungi, Candida glabrata was found as the most common agent. Susceptibility to daptomycin and linezolid was 100%, and meropenem, 91.4%. Highest antimicrobial resistance was found for ampicillin (77.47%) and moxifloxacin (72.89%). Nearly 49% of E. coli strains and 27% of Klebsiella pneumoniae strains showed extended-spectrum beta-lactamase (ESBL) production.
Bacterial UTI persists as one of the most common infections affecting all age groups and both genders. As in other countries, E. coli ranks first in Mexico, with 67.28%, and nearly 50% of the strains produce ESBL.
本研究的目的是描述墨西哥西部地区一家单中心三级转诊医院引起尿路感染（UTI）的微生物的患病率、微生物学特征、细菌耐药性及对抗生素的敏感性。
对2014年8月1日至2015年7月31日在微生物实验室处理的5895份培养样本进行分析。
共收集了5895份尿培养（UC）样本，其中3363份取自女性（57.05%），2532份取自男性（42.95%）。计算得出患病率为24%。从1444份阳性UC中分离出1512株微生物；主要病原体是大肠埃希菌，占67.28%，其次是铜绿假单胞菌，占7.12%。关于真菌，光滑念珠菌是最常见的病原体。对达托霉素和利奈唑胺的敏感性为100%，对美罗培南的敏感性为91.4%。氨苄西林（77.47%）和莫西沙星（72.89%）的耐药性最高。近49%的大肠埃希菌菌株和27%的肺炎克雷伯菌菌株产生超广谱β-内酰胺酶（ESBL）。
细菌性UTI仍然是影响所有年龄组和两性的最常见感染之一。与其他国家一样，大肠埃希菌在墨西哥排名第一，占67.28%，近50%的菌株产生ESBL。
