Advanced Centre for Research in High Energy Materials (ACRHEM), University of Hyderabad, Prof. C. R. Rao Road, Hyderabad 500046, Telangana, India.
Analyst. 2019 Mar 25;144(7):2327-2336. doi: 10.1039/c8an01276h.
Surface enhanced Raman spectroscopy (SERS) is a cutting edge analytical tool for trace analyte detection due to its highly sensitive, non-destructive and fingerprinting capability. Herein, we report the detection of multiple analytes from various mixtures using gold nanoparticles (NPs) and nanostructures (NSs) as SERS platforms. NPs and NSs were achieved through the simple approach of laser ablation in liquids (LAL) and their morphological studies were conducted with a UV-Visible absorption spectrometer, a high resolution transmission electron microscope (HRTEM) and a field emission scanning electron microscope (FESEM). The fabricated NPs/NSs allowed the sensitive and selective detection of different mixed compounds containing (i) rhodamine 6G (Rh6G) and methylene blue (MB), (ii) crystal violet (CV) and malachite green (MG), (iii) picric acid (explosive) and MB (dye), (iv) picric acid and 3-nitro-1,2,4- triazol-5-one (explosive, NTO) and (v) picric acid and 2,4-dinitrotoluene (explosive, DNT) using a portable Raman spectrometer. Thus, the obtained results demonstrate the capability of fabricated SERS substrates in identifying explosives and dyes from various mixtures. This could pave a new way for simultaneous detection of multiple analytes in real field applications.
表面增强拉曼光谱（SERS）是一种用于痕量分析物检测的前沿分析工具，因为它具有高度灵敏、非破坏性和指纹识别能力。在此，我们报告了使用金纳米粒子（NPs）和纳米结构（NSs）作为 SERS 平台从各种混合物中检测多种分析物。通过简单的液体激光烧蚀（LAL）方法获得 NPs 和 NSs，并通过紫外-可见吸收光谱仪、高分辨率透射电子显微镜（HRTEM）和场发射扫描电子显微镜（FESEM）进行形态研究。所制备的 NPs/NSs 允许对含有（i）罗丹明 6G（Rh6G）和亚甲蓝（MB）、（ii）结晶紫（CV）和孔雀石绿（MG）、（iii）苦味酸（爆炸物）和 MB（染料）、（iv）苦味酸和 3-硝基-1,2,4-三唑-5-酮（爆炸物，NTO）和（v）苦味酸和 2,4-二硝基甲苯（爆炸物，DNT）的不同混合化合物进行灵敏和选择性检测便携式拉曼光谱仪。因此，所得结果证明了所制备的 SERS 基底在识别各种混合物中的爆炸物和染料的能力。这可能为实际现场应用中同时检测多种分析物开辟了新途径。
