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短种植体(≤8mm)支持的下颌固定式和可摘式全颌修复体:系统评价和荟萃分析。

Fixed and Removable Full-Arch Restorations Supported by Short (≤ 8-mm) Dental Implants In the Mandible: A Systematic Review and Meta-Analysis.

出版信息

Int J Oral Maxillofac Implants. 2019 July/August;34(4):873–885. doi: 10.11607/jomi.7241. Epub 2019 Feb 15.

Abstract

PURPOSE

To evaluate, through a systematic review of the literature, the published data regarding marginal bone loss, implant failure proportion, biologic and prosthetic complications, and risk factors associated with short (≤ 8-mm) implants supporting fixed or removable full-arch restorations in the edentulous mandible.

MATERIALS AND METHODS

Two reviewers performed a search of five databases, with handsearching through the reference lists and grey literature. Controlled clinical trials and prospective cohort studies were selected in a two-phase process. The data were independently gathered for the same two reviewers. Quality assessment of the studies was done using the Cochrane Handbook for Systematic Reviews of Interventions for Randomized Clinical Trials and the Newcastle-Ottawa Scale for Prospective Cohort Studies. Marginal bone loss and Implant failure proportion were meta-analyzed using random (R-Em) and fixed-effects models (FEm), respectively, with a 95% confidence interval. A descriptive analysis was performed of the prevalence of biologic and prosthetic complications. Meta-regression analysis was run as fixed-effect models for risk factors.

RESULTS

Six studies met the eligibility criteria and had data extracted. A total of 291 short implants (lengths 5 to 8 mm) were placed in 122 patients (82 females; mean age, 64.7 ± 10.8) supporting 23 fixed and 99 removable full-arch restorations. The pooled marginal bone loss overall was 0.12 mm (0.07 to 0.17 mm). Marginal bone loss for fixed full-arch restorations was 0.11 mm (0.01 to 0.21 mm) and for removable full-arch restorations was 0.14 mm (0.07 to 0.21 mm). The pooled implant failure proportion was 2.0% (1.0% to 5.0%) for the overall studies. Implant failure proportion for fixed and removable restorations was 2.0% with a confidence interval of (0.0% to 9%) and (0.0% to 6%), respectively. The prevalence of prosthetic complications was 34.5% for fixed restorations and 2.6% for removable restorations. No biologic complications were found for fixed restorations, while 13.1% of removable restorations did have biologic complications. Risk factors did not demonstrate statistical differences regarding Implant failure proportion and marginal bone loss. All included studies demonstrated a high methodological quality.

CONCLUSION

Findings from this systematic review and meta-analysis suggest that full-arch restorations supported by short implants in atrophic edentulous mandibles might be a viable treatment option, presenting minimal marginal bone loss and implant failure in the short-term. However, further well-performed prospective clinical trials with long-term observation are needed.

摘要

目的

通过对文献的系统回顾评估,报告有关牙槽骨丧失、种植体失败比例、生物和修复体并发症以及与支持无牙下颌固定或可摘全口义齿修复的短(≤8mm)种植体相关的风险因素的已发表数据。

材料和方法

两名审查员进行了五项数据库的检索,并通过参考列表和灰色文献进行了手工搜索。选择了两阶段过程中的对照临床试验和前瞻性队列研究。数据由同两名审查员独立收集。使用 Cochrane 干预系统评价手册和纽卡斯尔-渥太华量表对研究进行质量评估。使用随机(R-Em)和固定效应模型(FEm)分别对边缘骨丢失和种植体失败比例进行荟萃分析,置信区间为 95%。对生物和修复体并发症的发生率进行描述性分析。使用固定效应模型对风险因素进行元回归分析。

结果

符合纳入标准并提取数据的研究有 6 项。共植入 291 枚短种植体(长度 5-8mm),植入 122 名患者(82 名女性;平均年龄 64.7±10.8),支持 23 个固定全口义齿修复体和 99 个可摘全口义齿修复体。总体边缘骨丢失为 0.12mm(0.07-0.17mm)。固定全口义齿修复体的边缘骨丢失为 0.11mm(0.01-0.21mm),可摘全口义齿修复体的边缘骨丢失为 0.14mm(0.07-0.21mm)。总体研究中种植体失败比例为 2.0%(1.0%-5.0%)。固定修复体和可摘修复体的种植体失败比例分别为 2.0%,置信区间为(0.0%-9%)和(0.0%-6%)。固定修复体的修复体并发症发生率为 34.5%,可摘修复体的发生率为 2.6%。固定修复体无生物学并发症,而 13.1%的可摘修复体有生物学并发症。风险因素在种植体失败比例和边缘骨丢失方面没有显示统计学差异。所有纳入的研究都具有较高的方法学质量。

结论

本系统评价和荟萃分析的结果表明,在牙槽骨萎缩的无牙下颌中,由短种植体支持的全口义齿修复可能是一种可行的治疗选择,在短期内表现出最小的边缘骨丢失和种植体失败。然而,需要进一步进行设计良好的长期前瞻性临床试验。

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