Peçanha L M, Assreuy Filho J, Cordeiro R S
Sector of Pharmacology, Universidade do Estado do Rio de Janeiro, Brazil.
Ann Trop Med Parasitol. 1988 Oct;82(5):429-36. doi: 10.1080/00034983.1988.11812272.
Mice infected with Plasmodium berghei, during the ten days of infection, showed significant pulmonary oedema, delayed activated partial thromboplastin time, augmented plasma fibrinolytic activity, oscillations in fibrinogen and unchanged plasminogen levels. These alterations can be expected to cause the release of inflammatory peptides, leading to increased vascular permeability and the generation and/or maintenance of the pronounced pulmonary oedema affecting these animals.
感染伯氏疟原虫的小鼠在感染的十天内出现了显著的肺水肿、活化部分凝血活酶时间延长、血浆纤维蛋白溶解活性增强、纤维蛋白原波动以及纤溶酶原水平不变。这些改变可能会导致炎性肽的释放，从而导致血管通透性增加以及影响这些动物的明显肺水肿的产生和/或维持。
