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治疗隐静脉移植物病变:药物洗脱支架不是答案!

Treating saphenous vein graft lesions: Drug-eluting stents are not the answer!

机构信息

Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota.

出版信息

Catheter Cardiovasc Interv. 2019 Feb 15;93(3):E193-E194. doi: 10.1002/ccd.28011.

DOI:10.1002/ccd.28011
PMID:30770658
Abstract

Saphenous vein graft (SVG) percutaneous coronary intervention carries high rates of acute (no reflow and periprocedural myocardial infarction) and long-term (restenosis and re-occlusion) complications. Long-term follow-up from the two largest trials of drug-eluting vs. bare metal stents in SVG lesions (The Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein graft Angioplasty and Is Drug-Eluting-Stenting Associated with Improved Results in Coronary Artery Bypass Grafts? Trial) definitely show no difference between the two stent types, suggesting that bare metal stents should be preferred given lower cost. Since SVG stenting remains associated with high failure rates, alternative treatment strategies, such as intervention of the corresponding native coronary artery lesions, may represent the future direction of the field.

摘要

大隐静脉桥血管(SVG)经皮冠状动脉介入术具有较高的急性(无复流和围手术期心肌梗死)和长期(再狭窄和再闭塞)并发症发生率。来自最大的两个药物洗脱支架与金属裸支架治疗 SVG 病变的临床试验(药物洗脱支架与金属裸支架在大隐静脉桥血管成形术中的比较及药物洗脱支架是否与冠状动脉旁路移植术的更好结果相关?试验)的长期随访结果明确显示两种支架类型之间没有差异,这表明由于成本较低,应首选金属裸支架。由于 SVG 支架置入术的失败率仍然较高,因此替代治疗策略,如干预相应的原生冠状动脉病变,可能代表该领域的未来发展方向。

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