多发性椎体骨折为全身性肥大细胞增多症的首发表现。
Multiple vertebral fractures as the first manifestation of systemic mastocytosis.
机构信息
Rheumatology, Hospitales San Roque Las Palmas De Gran Canaria, Las Palmas, Spain.
Rheumatology, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas, Spain.
出版信息
Osteoporos Int. 2019 May;30(5):1121-1124. doi: 10.1007/s00198-019-04897-9. Epub 2019 Feb 15.
PMID:30770937
Abstract
Systemic mastocytosis is a clonal disease of the mast cell progenitors of the bone marrow. The clinical picture varies from asymptomatic (indolent) to highly aggressive (mast cell leukemia). Up to one-third of patients with SM have osteoporosis and fractures. The following is an analysis of the case of a young patient with multiple fractures as the first manifestation of SM.
摘要
系统性肥大细胞增多症是骨髓中肥大细胞祖细胞的克隆性疾病。临床表现从无症状（惰性）到高度侵袭性（肥大细胞白血病）不等。多达三分之一的 SM 患者有骨质疏松症和骨折。以下是一例以多发性骨折为首发表现的年轻 SM 患者的病例分析。
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