Dickinson R G, Hooper W D, Pendlebury S C, Moses D, Eadie M J
Department of Medicine, University of Queensland.
Clin Exp Neurol. 1988;25:127-33.
Continuing experience with oxcarbazepine has shown that the drug tends to be less sedative than carbamazepine and at least as potent as an anticonvulsant but much more likely to cause hyponatraemia. The behaviour of the clearance of oxcarbazepine over a period of 3 months raises the possibility that the drug may not be as active an inducer of drug metabolism as is carbamazepine.
奥卡西平的持续应用经验表明，与卡马西平相比，该药的镇静作用往往较弱，作为抗惊厥药的效力至少相当，但更易导致低钠血症。奥卡西平在3个月期间的清除情况表明，该药作为药物代谢诱导剂的活性可能不如卡马西平。
