微阵列免疫诊断法在气传过敏原检测中的应用。
Microarray Immunodiagnostics for Aeroallergens.
机构信息
Personalized Medicine, Asthma and Allergy, Humanitas Research Hospital, Rozzano, MI, Italy.
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, MI, Italy.
出版信息
Curr Allergy Asthma Rep. 2019 Feb 15;19(1):10. doi: 10.1007/s11882-019-0832-z.
PURPOSE OF REVIEW
The impact of new technologies, especially multiplexed molecular allergy diagnostics based on allergen arrays, on the management of complex patients with respiratory allergies has been important.
RECENT FINDINGS
Currently, the detailed characteristics of the IgE profile of the patient, such as sensitization to genuine or cross-reacting components or the sensitization to potentially harmful allergens, allow an allergist to tailor treatment in the context of precision medicine rules. A number of relevant articles have been published in recent years on this topic, and, in this review, the new added values of allergen array-based diagnostics are reported.
目的综述
新技术，尤其是基于过敏原芯片的多重分子过敏诊断技术，对管理呼吸道过敏的复杂患者具有重要影响。
最近的发现
目前，患者 IgE 谱的详细特征，如对真实或交叉反应成分的致敏，或对潜在有害过敏原的致敏，使过敏专家能够根据精准医疗规则定制治疗方案。近年来，关于这一主题发表了许多相关文章，本综述报告了基于过敏原芯片的诊断技术的新附加值。
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