Department of Research and Development, Mental Health and Addiction, Vestre Viken Hospital Trust, Drammen, Norway; University of Oslo, Oslo, Norway.
Norwegian Institute of Public Health, Oslo, Norway.
J Affect Disord. 2019 Apr 15;249:112-120. doi: 10.1016/j.jad.2019.02.022. Epub 2019 Feb 7.
Suicide prevention is a core task in mental health services. Our objective was to determine whether Collaborative Assessment and Management of Suicidality (CAMS) reduced suicidal thoughts and behaviors and mental health distress more effectively than treatment as usual (TAU) in a heterogeneous patient population within specialized mental health care services.
In this observer-blinded pragmatic randomized controlled trial participants who scored 13 or above on Beck's Scale for Suicide Ideation-Current (BSSI-C) were included from seven in- and outpatient units. Primary outcome was suicidal ideation (BSSI-C). Secondary outcomes were mental health distress measured by the Outcome Questionnaire-45, and suicidal behaviors measured by the Suicide Attempt Self-Injury Count. Patients were assessed at baseline and after 6 and 12 months.
The final intent-to-treat analyses included 78 participants (mean age 35.9 years, SD = 14.5, 41 females). The majority were depressed (65%), had a secondary diagnosis (73%) and 32% suffered from borderline personality disorder or borderline traits. After 6 months, CAMS participants reported lower levels of suicidal ideation compared to TAU (β = -4.29, 95% CI = -8.32 to -0.27, p = .036). Larger changes in mental health distress were observed for CAMS participants after 6 months (β = -11.87, 95% CI = -22.99 to -0.76, p = .036) and 12 months (β = -13.70, 95% CI = -24.88 to -2.51, p = .017).
The modest sample size rendered the trial unable to detect small between-group differences.
CAMS reduced suicidal ideation and mental health distress more efficiently than TAU in a heterogeneous patient population within specialized care.
预防自杀是精神卫生服务的核心任务。我们的目的是确定在专门的精神卫生保健服务中,与常规治疗(TAU)相比,协作评估和管理自杀倾向(CAMS)是否能更有效地减少自杀意念和行为以及精神健康困扰,患者人群具有异质性。
在这项由观察者设盲的实用随机对照试验中,从七个门诊和住院单位中纳入 Beck 自杀意念当前量表(BSSI-C)评分为 13 或以上的参与者。主要结局是自杀意念(BSSI-C)。次要结局是通过结局问卷-45 测量的精神健康困扰,以及通过自杀企图自我伤害计数测量的自杀行为。患者在基线、6 个月和 12 个月时进行评估。
最终的意向治疗分析包括 78 名参与者(平均年龄 35.9 岁,标准差=14.5,41 名女性)。大多数人患有抑郁症(65%),有二级诊断(73%),32%患有边缘型人格障碍或边缘型特质。6 个月后,与 TAU 相比,CAMS 组参与者报告的自杀意念水平较低(β=-4.29,95%CI=-8.32 至 -0.27,p=0.036)。6 个月和 12 个月后,CAMS 组参与者的精神健康困扰变化较大(β=-11.87,95%CI=-22.99 至 -0.76,p=0.036)和 12 个月(β=-13.70,95%CI=-24.88 至 -2.51,p=0.017)。
样本量较小,使得试验无法检测到小的组间差异。
在专门护理中,CAMS 减少了异质患者人群的自杀意念和精神健康困扰,比 TAU 更有效。