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肥胖症手术治疗围手术期结局的种族差异。

Racial disparities in perioperative outcomes after bariatric surgery.

机构信息

Department of Surgery, University of Minnesota, Minneapolis, Minnesota.

Department of Surgery, University of Alabama, Birmingham, Alabama.

出版信息

Surg Obes Relat Dis. 2019 May;15(5):786-793. doi: 10.1016/j.soard.2018.12.021. Epub 2018 Dec 22.

Abstract

BACKGROUND

NonHispanic black patients bear a disproportionate burden of the obesity epidemic and its related medical co-morbidities. While bariatric surgery is the most effective treatment for morbid obesity, black patients access bariatric surgery at lower rates than nonHispanic white patients.

OBJECTIVES

To examine racial differences before bariatric surgery and in short-term perioperative outcomes and complications, and the extent to which race is independently associated with perioperative morbidity and mortality.

SETTING

Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program national database.

METHODS

Data were extracted from the 2015 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program Participant Use File. Multivariate analysis was used to identify differences in mortality, length of stay, readmission, and reintervention by race in patients undergoing laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy (SG).

RESULTS

A total of 108,198 patients were included in the analysis. There were significant differences in perioperative disease burden. Black patients had a higher body mass index at the time they underwent surgery (laparoscopic Roux-en-Y gastric bypass: 48.0 versus 45.7 kg/m; SG: 46.8 versus 44.9 kg/m; P < .001). Black patients had significantly longer length of stay and higher rates of readmission in both the laparoscopic Roux-en-Y gastric bypass and SG groups. In the SG group, black patients had significantly higher 30-day mortality (.2% versus .1%, odds ratio = 3.613, 95% confidence interval 1.990-6.558, P < .001) and higher rates of reoperation or reintervention.

CONCLUSIONS

We found significant racial disparities in bariatric surgery outcomes, including higher mortality in black patients undergoing SG. The specific causes of these disparities remain unclear and must be the subject of future research.

摘要

背景

非西班牙裔黑种人患者承受着肥胖流行及其相关的合并症的不成比例的负担。虽然减重手术是治疗病态肥胖最有效的方法,但黑种人患者接受减重手术的比例低于非西班牙裔白种人患者。

目的

检查减重手术前和短期围手术期结局和并发症的种族差异,以及种族与围手术期发病率和死亡率的独立相关性的程度。

设置

代谢和减重手术认证和质量改进计划国家数据库。

方法

从 2015 年代谢和减重手术认证和质量改进计划参与者使用文件中提取数据。使用多变量分析来确定接受腹腔镜 Roux-en-Y 胃旁路术或腹腔镜袖状胃切除术 (SG)的患者中种族之间死亡率、住院时间、再入院和再次干预的差异。

结果

共有 108198 名患者纳入分析。围手术期疾病负担存在显著差异。黑人患者在接受手术时的体重指数更高(腹腔镜 Roux-en-Y 胃旁路术:48.0 与 45.7 kg/m;SG:46.8 与 44.9 kg/m;P <.001)。黑人患者在腹腔镜 Roux-en-Y 胃旁路术和 SG 两组中的住院时间均较长,再入院率较高。在 SG 组中,黑人患者的 30 天死亡率显著更高(0.2%与 0.1%,比值比 = 3.613,95%置信区间 1.990-6.558,P <.001),并且再次手术或再次干预的发生率更高。

结论

我们发现减重手术结局存在显著的种族差异,包括 SG 中黑人患者的死亡率更高。这些差异的具体原因尚不清楚,必须成为未来研究的主题。

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Racial disparities in perioperative outcomes after bariatric surgery.肥胖症手术治疗围手术期结局的种族差异。
Surg Obes Relat Dis. 2019 May;15(5):786-793. doi: 10.1016/j.soard.2018.12.021. Epub 2018 Dec 22.

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