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Effect of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Roux-en-Y Gastric Bypass on Weight Loss in Patients With Morbid Obesity: The SM-BOSS Randomized Clinical Trial.腹腔镜袖状胃切除术与腹腔镜Roux-en-Y胃旁路术对病态肥胖患者体重减轻的影响:SM-BOSS随机临床试验
JAMA. 2018 Jan 16;319(3):255-265. doi: 10.1001/jama.2017.20897.
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Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study.糖尿病手术研究中,5年时生活方式干预与药物治疗联合或不联合Roux-en-Y胃旁路手术对糖化血红蛋白、低密度脂蛋白胆固醇和收缩压的控制情况
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JAMA. 2018 Jan 16;319(3):241-254. doi: 10.1001/jama.2017.20313.
4
Seven-Year Weight Trajectories and Health Outcomes in the Longitudinal Assessment of Bariatric Surgery (LABS) Study.七年体重轨迹与减肥手术纵向评估(LABS)研究中的健康结果。
JAMA Surg. 2018 May 1;153(5):427-434. doi: 10.1001/jamasurg.2017.5025.
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National Trends in Bariatric Surgery 2012-2015: Demographics, Procedure Selection, Readmissions, and Cost.2012 - 2015年减肥手术的全国趋势:人口统计学、手术选择、再入院情况及费用
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Implicit bias in healthcare professionals: a systematic review.医疗保健专业人员中的隐性偏见:一项系统综述。
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Enhanced Recovery after Bariatric Surgery: Systematic Review and Meta-Analysis.减重手术后的加速康复:系统评价与荟萃分析
Obes Surg. 2017 Jan;27(1):226-235. doi: 10.1007/s11695-016-2438-z.
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Racial disparities in adult all-cause and cause-specific mortality among us adults: mediating and moderating factors.美国成年人全因死亡率和特定病因死亡率的种族差异:中介和调节因素
BMC Public Health. 2016 Oct 22;16(1):1113. doi: 10.1186/s12889-016-3744-z.
10
American Society for Metabolic and Bariatric Surgery estimation of bariatric surgery procedures in 2015 and surgeon workforce in the United States.美国代谢与减重外科学会对2015年减重手术程序及美国外科医生人力的评估。
Surg Obes Relat Dis. 2016 Nov;12(9):1637-1639. doi: 10.1016/j.soard.2016.08.488. Epub 2016 Aug 26.

肥胖症手术治疗围手术期结局的种族差异。

Racial disparities in perioperative outcomes after bariatric surgery.

机构信息

Department of Surgery, University of Minnesota, Minneapolis, Minnesota.

Department of Surgery, University of Alabama, Birmingham, Alabama.

出版信息

Surg Obes Relat Dis. 2019 May;15(5):786-793. doi: 10.1016/j.soard.2018.12.021. Epub 2018 Dec 22.

DOI:10.1016/j.soard.2018.12.021
PMID:30772252
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11922185/
Abstract

BACKGROUND

NonHispanic black patients bear a disproportionate burden of the obesity epidemic and its related medical co-morbidities. While bariatric surgery is the most effective treatment for morbid obesity, black patients access bariatric surgery at lower rates than nonHispanic white patients.

OBJECTIVES

To examine racial differences before bariatric surgery and in short-term perioperative outcomes and complications, and the extent to which race is independently associated with perioperative morbidity and mortality.

SETTING

Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program national database.

METHODS

Data were extracted from the 2015 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program Participant Use File. Multivariate analysis was used to identify differences in mortality, length of stay, readmission, and reintervention by race in patients undergoing laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy (SG).

RESULTS

A total of 108,198 patients were included in the analysis. There were significant differences in perioperative disease burden. Black patients had a higher body mass index at the time they underwent surgery (laparoscopic Roux-en-Y gastric bypass: 48.0 versus 45.7 kg/m; SG: 46.8 versus 44.9 kg/m; P < .001). Black patients had significantly longer length of stay and higher rates of readmission in both the laparoscopic Roux-en-Y gastric bypass and SG groups. In the SG group, black patients had significantly higher 30-day mortality (.2% versus .1%, odds ratio = 3.613, 95% confidence interval 1.990-6.558, P < .001) and higher rates of reoperation or reintervention.

CONCLUSIONS

We found significant racial disparities in bariatric surgery outcomes, including higher mortality in black patients undergoing SG. The specific causes of these disparities remain unclear and must be the subject of future research.

摘要

背景

非西班牙裔黑种人患者承受着肥胖流行及其相关的合并症的不成比例的负担。虽然减重手术是治疗病态肥胖最有效的方法,但黑种人患者接受减重手术的比例低于非西班牙裔白种人患者。

目的

检查减重手术前和短期围手术期结局和并发症的种族差异,以及种族与围手术期发病率和死亡率的独立相关性的程度。

设置

代谢和减重手术认证和质量改进计划国家数据库。

方法

从 2015 年代谢和减重手术认证和质量改进计划参与者使用文件中提取数据。使用多变量分析来确定接受腹腔镜 Roux-en-Y 胃旁路术或腹腔镜袖状胃切除术 (SG)的患者中种族之间死亡率、住院时间、再入院和再次干预的差异。

结果

共有 108198 名患者纳入分析。围手术期疾病负担存在显著差异。黑人患者在接受手术时的体重指数更高(腹腔镜 Roux-en-Y 胃旁路术:48.0 与 45.7 kg/m;SG:46.8 与 44.9 kg/m;P <.001)。黑人患者在腹腔镜 Roux-en-Y 胃旁路术和 SG 两组中的住院时间均较长,再入院率较高。在 SG 组中,黑人患者的 30 天死亡率显著更高(0.2%与 0.1%,比值比 = 3.613,95%置信区间 1.990-6.558,P <.001),并且再次手术或再次干预的发生率更高。

结论

我们发现减重手术结局存在显著的种族差异,包括 SG 中黑人患者的死亡率更高。这些差异的具体原因尚不清楚,必须成为未来研究的主题。