Teixeira Filipa, Fonseca Ana Cláudia, Pinto Filomena
Hospital de Santa Maria, Lisboa, Portugal; Clínica Universitária de Oftalmologia, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Hospital de Santa Maria, Lisboa, Portugal; Clínica Universitária de Oftalmologia, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
J AAPOS. 2019 Jun;23(3):178-179. doi: 10.1016/j.jaapos.2019.01.012. Epub 2019 Feb 14.
Acquired myelinated retinal nerve fibers (MRNF) is rare. The reported cases occur after optic disk injuries. We describe a case of a patient with neurofibromatosis type 1 and bilateral optic pathway glioma, who after 3 years' follow-up developed unilateral MRNF. Optical coherence tomography of the optic nerve disclosed progressive increased thickness and hyper-reflectivity of the peripapillary retinal nerve fiber layer associated with the myelinization process. Although the patient remains asymptomatic, myelinization continues to progress.
获得性髓鞘视网膜神经纤维（MRNF）较为罕见。已报道的病例发生在视盘损伤之后。我们描述了一例患有1型神经纤维瘤病和双侧视神经通路胶质瘤的患者，在3年的随访后出现了单侧MRNF。视神经的光学相干断层扫描显示，与髓鞘形成过程相关的视乳头周围视网膜神经纤维层厚度逐渐增加且反射增强。尽管该患者仍无症状，但髓鞘形成仍在继续进展。
