Xu X B, Zhao L X, Li Y Q, He Y L
Institute of Environmental Chemistry, Academia Sinica, Beijing, China.
Biomed Environ Sci. 1988 Jun;1(1):83-9.
Five commercially available nitropolyclyclic aromatic hydrocarbons (nitro-PAH), namely, 4-nitrobiphenyl, 2-nitrofluorene, 9-nitroanthracene, 1-nitropyrene, and 2,7-dinitrofluorene, were exposed under restricted sunlight in the open air. The direct-acting mutagenicities of the samples after an exposure of 45 days were measured in order to compare them with those of the original samples in the Ames Salmonella typhimurium bioassay. It was found that the mutagenicities of some nitro-PAH do not change significantly while the mutagenicities of others increase or decrease after exposure. A preliminary study of nitro-PAH reaction products after exposure using GC, GC/MS, and FT-IR is also reported.
五种市售的硝基多环芳烃（nitro-PAH），即4-硝基联苯、2-硝基芴、9-硝基蒽、1-硝基芘和2,7-二硝基芴，在露天有限阳光照射下进行暴露实验。在鼠伤寒沙门氏菌艾姆斯试验中，测量暴露45天后样品的直接致突变性，以便与原始样品的致突变性进行比较。结果发现，一些硝基多环芳烃的致突变性在暴露后没有显著变化，而其他一些则增加或降低。还报道了使用气相色谱（GC）、气相色谱/质谱联用（GC/MS）和傅里叶变换红外光谱（FT-IR）对暴露后硝基多环芳烃反应产物的初步研究。
