Aoun Joe, Hatab Taha, Volpi John, Lin Chun Huie
Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA.
Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA.
Interv Cardiol Clin. 2025 Jul;14(3):395-410. doi: 10.1016/j.iccl.2024.09.001.
Patent foramen ovale (PFO) and atrial septal defects (ASDs) are two types of interatrial communications with unique clinical presentations and management strategies. The PFO is a normal part of fetal development that typically closes shortly after birth but may persist in as many as 25% to 30% of adults. The communication between atria may result in paradoxic embolism and embolic stroke. On the other hand, ASDs (anatomically defined as secundum, primum, sinus venosus, and coronary sinus in order of prevalence) typically result in right heart volume overload and are often associated with other congenital defects. The diagnostic methods, treatment options including surgical and percutaneous approaches, and potential complications are described. Both conditions underline the significance of precise diagnosis and appropriate management to mitigate risks and ensure optimal patient outcomes.
卵圆孔未闭(PFO)和房间隔缺损(ASD)是两种具有独特临床表现和治疗策略的心房内交通类型。卵圆孔未闭是胎儿发育的正常部分,通常在出生后不久闭合,但在多达25%至30%的成年人中可能持续存在。心房之间的交通可能导致反常栓塞和栓塞性中风。另一方面,房间隔缺损(按发生率依次在解剖学上定义为继发孔、原发孔、静脉窦型和冠状窦型)通常导致右心容量负荷过重,并且常与其他先天性缺陷相关。文中描述了诊断方法、包括手术和经皮方法在内的治疗选择以及潜在并发症。这两种情况都突显了精确诊断和适当管理对于降低风险和确保患者获得最佳预后的重要性。