磁共振成像灌注技术在兔跟腱损伤评估中的应用

MAGNETIC RESONANCE IMAGING PERFUSION TECHNIQUE IN THE EVALUATION OF ACHILLES TENDON INJURY IN RABBITS.

作者信息

Tavares Wilson Campos, Paulino Eduardo, Magalhaes Maria Angélica Baron, Fonseca Ana Clara Guimarães Gabrich, Rodrigues João Bernardo Sancio Rocha, Resende Vivian

机构信息

Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG), Department of Surgery, Belo Horizonte, MG, Brazil.

Faculdade de Medicina da Universidade Federal de Minas Gerais (UFMG), Departamento de Anatomia Patológica, Belo Horizonte, MG, Brazil.

出版信息

Acta Ortop Bras. 2019 Jan-Feb;27(1):12-15. doi: 10.1590/1413-785220192701132230.

DOI:10.1590/1413-785220192701132230

PMID:30774522

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6362701/

Abstract

OBJECTIVE

This study aimed to evaluate the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the experimental model of Achilles tendon injury.

METHODS

Twelve white male adults New Zealand rabbits were divided into two groups, a group with resection of the central portion of the Achilles tendon (n = 8) and a control group (n = 4). Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) was performed 4 weeks after the surgical procedure, followed by histological analysis of the tendons.

RESULTS

The main finding of this study was the difference (p < 0.001) in peak contrast enhancement on DCE-MRI, which demonstrated that the operated group had greater contrast uptake. The operated tendons showed histological disruption of their architecture, and cluttered appearance of tendinous fibers, with vascular and fibroblast proliferations.

CONCLUSION

DCE-MRI is a technique with a potential to demonstrate changes in the vascularity pattern of the Achilles tendon before and after operation. DCE-MRI has a potential to be used in studies of tendinosis diagnosis and surgical follow-up. .

摘要