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放射性碘(I - 131)治疗隔离室:在墙上设置铅玻璃窗,以提高患者舒适度并营造更好的环境氛围。

Radioactive iodine (I-131) therapy isolation rooms: Introduction of lead glass window on the wall for patient comfort and better ambience.

作者信息

Al Aamri Marwa, Ravichandran Ramamoorthy, Al Balushi Naima

机构信息

Department of Nuclear Medicine, Molecular Imaging Center, Royal Hospital, Muscat, Sultanate of Oman.

Department of Radiation Oncology, Medical Physics Unit, Cachar Cancer Hospital and Research Centre, Silchar, Assam, India.

出版信息

World J Nucl Med. 2019 Jan-Mar;18(1):42-44. doi: 10.4103/wjnm.WJNM_18_18.

DOI:10.4103/wjnm.WJNM_18_18
PMID:30774545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6357721/
Abstract

For administration of radioactive iodine for the treatment of differentiated cancer thyroid patients, activities ranging between 1.85GBq and 7.0GBq are used. The construction of concrete rooms cleared by national regulatory authorities do not recommend the presence of windows on the walls or advise same lead equivalence of wall for the lead glass if they are put on the walls. To avoid phobia of patients to give consent for I-131 treatment and to stay in isolation rooms, a necessity was felt to introduce glass window on the opposite side wall of entrance door, which had a service corridor with restricted entry, opening toward garden area. Commercially available lead glass used for X-ray computed tomography scanner was fixed on the 0.35 m thick concrete wall in two rooms. The adequacy of protection offered by the lead glass was determined. A I-131 capsule 600 MBq was moved at a distance 50 cm away from the wall inside the room, and transmitted radiation was measured outside the room. An end window pancake type, beta-gamma survey meter was used. The measured values were normalized for 3.7 GBq at 2 m bed position in μSv/h. The obtained maximum exposure rate was 1.48 μSv/h transmitted from the glass window, against 0.44 μSv/h transmitted at full concrete wall level. As the patients provide shielding to the administrated activity, also the activity is progressively decreasing fast with an effective half-life, the stray radiation levels will be decreasing outside, reducing the mean radiation level to 0.74 μSv/h, and increasing the efficacy of protection. The patient's bed position is at lower level by 0.5 m from the lower edge of the lead glass, so that during patient is in bed the stray radiation levels reduce further. As there are no reports about such facility for isolation rooms, this report may be of value in health physics literature.

摘要

对于分化型甲状腺癌患者放射性碘治疗,使用的活度范围在1.85GBq至7.0GBq之间。经国家监管机构批准建造的混凝土房间,不建议墙壁上有窗户,若在墙上安装铅玻璃,则建议其与墙体具有相同的铅当量。为避免患者因恐惧而拒绝I - 131治疗并入住隔离病房,人们觉得有必要在入口门对面的侧墙上设置玻璃窗,该侧墙有一条限制进入的服务走廊,并朝向花园区域。将用于X射线计算机断层扫描仪的市售铅玻璃安装在两个房间0.35米厚的混凝土墙上。测定了铅玻璃提供的防护充分性。将一个600MBq的I - 131胶囊在房间内距离墙壁50厘米处移动,在房间外测量透射辐射。使用了一种端窗煎饼型β - γ测量仪。测量值在2米床位处针对3.7GBq进行归一化,单位为μSv/h。从玻璃窗透射获得的最大暴露率为1.48μSv/h,而在完整混凝土墙水平透射率为0.44μSv/h。由于患者对所施用的活度起到屏蔽作用,且活度随着有效半衰期迅速下降,外部的杂散辐射水平将会降低,平均辐射水平降至0.74μSv/h,防护效果增强。患者床位比铅玻璃下边缘低0.5米,这样患者卧床时杂散辐射水平会进一步降低。由于尚无关于隔离病房此类设施的报告,本报告在健康物理学文献中可能具有价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa0/6357721/b8a0981db5bb/WJNM-18-42-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa0/6357721/a81d9f997cfa/WJNM-18-42-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa0/6357721/b8a0981db5bb/WJNM-18-42-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa0/6357721/a81d9f997cfa/WJNM-18-42-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa0/6357721/b8a0981db5bb/WJNM-18-42-g002.jpg

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本文引用的文献

1
Radioactive (131)Iodine Body Burden and Blood Dose Estimates in Treatment for Differentiated Thyroid Cancer by External Probe Counting.通过外部探头计数对分化型甲状腺癌治疗中放射性(131)碘体内负荷和血液剂量的估计
World J Nucl Med. 2016 Sep;15(3):153-60. doi: 10.4103/1450-1147.174701.
2
Therapeutic applications of radioactive (131)iodine: Procedures and incidents with capsules.放射性(131)碘的治疗应用:胶囊的操作与事件
Indian J Nucl Med. 2016 Jul-Sep;31(3):176-8. doi: 10.4103/0972-3919.183603.
3
Radioactive body burden measurements in (131)iodine therapy for differentiated thyroid cancer: effect of recombinant thyroid stimulating hormone in whole body (131)iodine clearance.
分化型甲状腺癌碘-131治疗中放射性体内负荷测量:重组促甲状腺激素对全身碘-131清除的影响
World J Nucl Med. 2014 Jan;13(1):56-61. doi: 10.4103/1450-1147.138576.
4
An overview of radioactive waste disposal procedures of a nuclear medicine department.核医学科放射性废物处理程序概述。
J Med Phys. 2011 Apr;36(2):95-9. doi: 10.4103/0971-6203.79692.
5
Development of departmental standard for traceability of measured activity for I-131 therapy capsules used in nuclear medicine.制定核医学中用于I-131治疗胶囊的测量活性可追溯性的部门标准。
J Med Phys. 2011 Jan;36(1):46-50. doi: 10.4103/0971-6203.75472.
6
Estimation of effective half life of clearance of radioactive Iodine (I) in patients treated for hyperthyroidism and carcinoma thyroid.对接受甲状腺功能亢进症和甲状腺癌治疗的患者体内放射性碘(I)清除有效半衰期的估计。
Indian J Nucl Med. 2010 Apr;25(2):49-52. doi: 10.4103/0972-3919.72686.