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猫小脑和脑干的纤维软骨栓塞性脑病

Fibrocartilaginous embolic encephalopathy of the cerebellum and brainstem in a cat.

作者信息

McBride Rebecca, Rylander Helena, Lyman Douglas

机构信息

The Ohio State University Veterinary Hospital, 601 Vernon L Tharp St, Columbus, OH 43210, USA.

Veterinary Medical Teaching Hospital, University of Wisconsin-Madison, 2015 Linden Dr, Madison, WI 53706, USA.

出版信息

Open Vet J. 2018;8(4):489-492. doi: 10.4314/ovj.v8i4.22. Epub 2018 Dec 29.

DOI:10.4314/ovj.v8i4.22
PMID:30775290
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6356102/
Abstract

A 12-year old male castrated Siamese cat was evaluated for a one-day history of mild obtundation and decerebellate rigidity. Neurological examination findings were consistent with multifocal disease including lesions within the right cerebellum and right brainstem. Investigations included hematology, biochemistry, urinalysis, and urine culture. A definitive diagnosis was not achieved clinically and differential diagnoses included vascular disease, neoplasia, and infectious disease. About nine hours after admission, the cat had an episode where it became rigid and then limp. The cat became agonal and went into cardiopulmonary arrest and attempts of resuscitation were unsuccessful. Post-mortem examination revealed evidence of multiple fibrocartilaginous emboli (FCE) within the cerebellum and within meningeal vessels on the ventral aspect of the brainstem. This is the first reported case of fibrocartilaginous embolism causing an encephalopathy in a cat. While this is a rare disease, it is an important differential diagnosis that should be considered in cases of acute encephalopathies in cats.

摘要

一只12岁已去势的雄性暹罗猫因有一天的轻度昏迷和去大脑强直病史而接受评估。神经学检查结果与多灶性疾病相符,包括右侧小脑和右侧脑干内的病变。检查包括血液学、生物化学、尿液分析和尿培养。临床上未做出明确诊断,鉴别诊断包括血管疾病、肿瘤和传染病。入院约9小时后,这只猫出现一阵强直然后瘫软的情况。猫陷入濒死状态并发生心肺骤停,复苏尝试未成功。尸检显示小脑和脑干腹侧脑膜血管内有多个纤维软骨栓塞(FCE)的证据。这是首例报告的猫因纤维软骨栓塞导致脑病的病例。虽然这是一种罕见疾病,但在猫急性脑病病例中应考虑将其作为重要的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d2/6356102/dea70b35f413/OpenVetJ-8-489-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d2/6356102/59c3c17ce52f/OpenVetJ-8-489-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d2/6356102/dea70b35f413/OpenVetJ-8-489-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d2/6356102/59c3c17ce52f/OpenVetJ-8-489-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98d2/6356102/dea70b35f413/OpenVetJ-8-489-g002.jpg

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