Bristol Veterinary School, Faculty of Health Sciences, University of Bristol, Langford House, Langford, United Kingdom.
Pathology Department, Animal and Plant Health Agency, Weybridge, United Kingdom.
J Comp Pathol. 2020 Nov;181:58-62. doi: 10.1016/j.jcpa.2020.09.015. Epub 2020 Nov 3.
A 1-year-old boar was investigated after presenting with acute onset collapse and obtundance. No significant gross lesions were observed at post-mortem examination. Histopathological investigation revealed a severe bilateral and multifocal necrotizing encephalopathy with an amorphous material, which obstructed neuroparenchymal vessels in the metencephalon and mesencephalon. Alcian blue staining identified the material as of cartilaginous origin and a diagnosis of cerebral fibrocartilaginous embolism was established. No gross evidence of vertebral disc disease was detected and the origin of the embolic material was not found. Although cerebral fibrocartilaginous embolism has been reported in a human, and rarely in animals, it has not been reported previously in the pig.
一头 1 岁龄公猪出现急性发作性倒地和昏迷，前来就诊。剖检时未观察到明显的大体病变。组织病理学检查显示严重的双侧和多灶性坏死性脑病，伴有无定形物质，阻塞中脑和间脑的神经实质血管。阿尔辛蓝染色鉴定该物质来源于软骨，并确诊为脑纤维软骨栓塞。未发现椎间盘疾病的大体证据，也未找到栓子物质的来源。尽管脑纤维软骨栓塞在人类中已有报道，在动物中也很少见，但在猪中尚未有报道。
