Ou Ling-Chun, Chang Yin-Fan, Chang Chin-Sung, Chao Ting-Hsing, Lin Ruey-Mo, Sun Zih-Jie, Wu Chih-Hsing
Department of Family Medicine, Antai Medical Cooperation Tien Sheng Memorial Hospital, PingTung, Taiwan.
Department of Nursing, Meiho University, PingTung, Taiwan.
Osteoporos Sarcopenia. 2016 Dec;2(4):221-227. doi: 10.1016/j.afos.2016.10.004. Epub 2016 Dec 10.
Falls is a risk factor for fracture. The FRAX predicts fractures. Whether the FRAX is associated with fall in both gender is inconclusive. The aim of our study is to evaluate the association between FRAX scores and falls.
The cross-sectional study set from 2009 to 2010 included 1200 community-dwelling people who were systematically sampled in central Taiwan. The 1200 participants (men: 524; women: 676; ≥40 years old) completed questionnaires about socioeconomic status; lifestyle; medical and fall history were completed. FRAX scores with and without bone mineral density (BMD) were calculated by using the Taiwan calculator.
A total of 19.8% participants fell down. Binary regression models showed that diabetes mellitus history (OR: 1.61; 95% CI: 1.03-2.52), the FRAX without BMD in a continuous major score (OR: 1.06; 95% CI: 1.03-1.09), continuous hip score (OR: 1.11; 95% CI: 1.05-1.16), categorical major score ≥ 10% (OR: 1.81; 95% CI: 1.25-2.61), and categorical hip score ≥ 3% (OR: 1.80; 95% CI: 1.30-2.50) were independent risk factors for falls. FRAX with BMD in a continuous major score (OR: 1.04; 95% CI: 1.02-1.06), continuous hip score (OR: 1.06; 95% CI: 1.02-1.09), categorical major score ≥ 10% (OR: 1.52; 95% CI: 1.09-2.12), and categorical hip score ≥ 3% (OR: 1.53; 95% CI: 1.13-2.09) were also independent risk factors.
We concluded that FRAX scores with and without BMD were unanimously correlated with falls in community-dwelling middle-aged and elderly males and females.
跌倒为骨折的一个风险因素。FRAX可预测骨折。FRAX是否与两性的跌倒相关尚无定论。我们研究的目的是评估FRAX评分与跌倒之间的关联。
2009年至2010年的横断面研究纳入了1200名在台湾中部系统抽样的社区居民。这1200名参与者(男性524名;女性676名;年龄≥40岁)完成了关于社会经济状况、生活方式的问卷;完成了医疗和跌倒史问卷。使用台湾计算器计算有和没有骨密度(BMD)的FRAX评分。
共有19.8%的参与者跌倒。二元回归模型显示,糖尿病病史(比值比:1.61;95%置信区间:1.03 - 2.52)、连续主要评分中无BMD的FRAX(比值比:1.06;95%置信区间:1.03 - 1.09)、连续髋部评分(比值比:1.11;95%置信区间:1.05 - 1.16)、分类主要评分≥10%(比值比:1.81;95%置信区间:1.25 - 2.61)以及分类髋部评分≥3%(比值比:1.80;95%置信区间:1.30 - 2.50)是跌倒的独立风险因素。有BMD的FRAX在连续主要评分中(比值比:1.04;95%置信区间:1.02 - 1.06)、连续髋部评分(比值比:1.06;95%置信区间:1.02 - 1.09)、分类主要评分≥10%(比值比:1.52;95%置信区间:1.09 - 2.12)以及分类髋部评分≥3%(比值比:1.53;95%置信区间:1.13 - 2.09)也是独立风险因素。
我们得出结论,有和没有BMD的FRAX评分均与社区居住的中老年男性和女性的跌倒一致相关。