Department of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto, 615-8510, Japan.
National Institute of Technology, Suzuka College, Emeritus Professor, Kyoto University, Shiroko-cho, Suzuka, Mie, 510-0294, Japan.
Chemistry. 2019 Apr 1;25(19):4946-4950. doi: 10.1002/chem.201900743. Epub 2019 Mar 14.
Synthesis of ketones containing various functional groups from acid chlorides bearing electrophilic functional groups and functionalized organolithiums was achieved using a flow microreactor system. Extremely fast mixing is important for high chemoselectivity.
采用流微反应系统，从带有亲电官能团的酰氯和功能化有机锂合成了含有各种官能团的酮。快速混合对于高化学选择性非常重要。
