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患有神经管及其他中枢神经系统缺陷胎儿的下肢运动与泌尿功能

Lower limb movements and urologic function in fetuses with neural tube and other central nervous system defects.

作者信息

Warsof S L, Abramowicz J S, Sayegh S K, Levy D L

机构信息

Division of Maternal-Fetal Medicine, Eastern Virginia Medical School, Norfolk.

出版信息

Fetal Ther. 1988;3(3):129-34. doi: 10.1159/000263344.

DOI:10.1159/000263344
PMID:3077584
Abstract

Lower limb movements and urologic systems were evaluated by prenatal ultrasound in 120 fetuses with either neural tube defects or intracranial anomalies. Despite anticipated major lower extremity and bladder dysfunction, lower limb movements were seen in 100% of the fetuses with anencephaly and encephaloceles, 93% with isolated spina bifida, 60% with complex spina bifida and 90% with abnormal intracranial findings. In all the cases except those with cloacal exstrophy, fetal bladder and collecting systems appeared normal. Therefore, fetal lower limb movements and urinary tract integrity appear to have no diagnostic or prognostic value in fetuses with neural tube defects or other central nervous system anomalies. These diagnoses can only be made by direct ultrasound observation of the lesion itself.

摘要

对120例患有神经管缺陷或颅内异常的胎儿进行产前超声检查,评估其下肢运动和泌尿系统情况。尽管预计会出现严重的下肢和膀胱功能障碍,但无脑儿和脑膨出胎儿中有100%出现下肢运动,单纯脊柱裂胎儿中有93%出现下肢运动,复杂脊柱裂胎儿中有60%出现下肢运动,颅内检查异常的胎儿中有90%出现下肢运动。除泄殖腔外翻外,所有病例的胎儿膀胱和集合系统均显示正常。因此,对于患有神经管缺陷或其他中枢神经系统异常的胎儿,胎儿下肢运动和尿路完整性似乎没有诊断或预后价值。这些诊断只能通过直接超声观察病变本身来做出。

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Fetal Ther. 1988;3(3):129-34. doi: 10.1159/000263344.
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Approximate entropy values demonstrate impaired neuromotor control of spontaneous leg activity in infants with myelomeningocele.近似熵值表明脊髓脊膜膨出婴儿的自发腿部活动存在神经运动控制受损。
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